Evidence map›Paper›PMID 30489341›Full record

ArticleFemale pelvic medicine & reconstructive surgery2020

Pelvic Pain and Apical Prolapse Surgery: A Population-Based Retrospective Cohort Study.

Mostafa A Borahay, Burak Zeybek, Parin Patel, Yu-Li Lin, Yong-Fang Kuo, Gokhan S Kilic

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Article in Female pelvic medicine & reconstructive surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Mostafa A BorahayFrom the Department of Gynecology & Obstetrics, Johns Hopkins University, Baltimore, MD.
Burak ZeybekDepartment of Obstetrics and Gynecology, Yale University, New Haven, CT.
Parin PatelDepartments of Obstetrics and Gynecology.
Yu-Li LinPreventive Medicine and Community Health, the University of Texas Medical Branch, Galveston, TX.
Yong-Fang KuoPreventive Medicine and Community Health, the University of Texas Medical Branch, Galveston, TX.
Gokhan S KilicDepartments of Obstetrics and Gynecology.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Mechanisms of actions(s) of simvastatin in uterine leiomyomaR01HD094380 · NICHD · JOHNS HOPKINS UNIVERSITY · PI BORAHAY, MOSTAFA A. · 2018 to 2022
$4.0M
NCATS NIH HHS UL1 TR001863NICHD NIH HHS R01 HD094380
6 · The paper itself

Abstract

objectivesThe aims of this study were to evaluate the association of preoperative pelvic pain with operative characteristics and the association of patient and operative characteristics with postoperative pain.

methodsThis is a retrospective cohort study utilizing Clinformatics DataMart, a large national commercial insurance database. We collected data for patients older than 18 years who underwent apical prolapse surgery between January 2005 and December 2014. We stratified data by preoperative (prior) pain and analyzed for associations of prior and postoperative pain. Logistic regression analysis was performed using SAS software.

resultsA total of 14,440 patients met inclusion criteria and were analyzed. Patients with prior pain were more likely to have an abdominal (open or laparoscopic) approach, a concomitant hysterectomy, but less likely to have additional repairs or a mesh insertion (P < 0.001). Postoperative pain was less with a concomitant hysterectomy, whether they had prior pain (odds ratio [OR], 0.56; 95% confidence interval [CI], 0.41-0.77) or not (OR, 0.68; 95% CI, 0.56-0.82). Additional vaginal repairs were associated with more postoperative pain for those without prior pain (OR, 1.63; 95% CI, 1.3-2.04). Age older than 45 years was associated with less pain. Length of hospital stay of more than 2 days was associated with more pain.

conclusionsPatients with prior pain were more likely to undergo an abdominal approach and have a concomitant hysterectomy. Postoperative pain was less with a concomitant hysterectomy, but more with additional vaginal repairs. There is a need to include pain as an outcome in future studies, particularly clinical trials.

Indexed as

AdultAgedDatabases, FactualFemaleGynecologic Surgical ProceduresHumansLength of StayMiddle AgedPelvic Organ ProlapsePelvic PainPostoperative PainPreoperative PeriodRetrospective StudiesSeverity of Illness Index

Identifiers

PMID30489341
PMCPMC6536368

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