Evidence map›Paper›PMID 30489116›Full record

ArticleNeuropsychology2019

Semantic network function captured by word frequency in nondemented APOE ε4 carriers.

Jet M J Vonk, Roxanna J Flores, Dayanara Rosado, Carolyn Qian, Raquel Cabo, Josina Habegger, Karmen Louie, Elizabeth Allocco, Adam M Brickman, Jennifer J Manly

Open access · hybridAbstract read
In one paragraph

Article in Neuropsychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Benchmarking speech biomarkers of Alzheimer's against cognitive and neural measures.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  7. Article
  8. Multivariate word properties in fluency tasks reveal markers of Alzheimer's dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
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  20. Sensitive Measures of Cognition in Mild Cognitive Impairment.Journal of Alzheimer's disease : JAD · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jet M J VonkTaub Institute for Research on Alzheimer's Disease and the Aging Brain.ORCID 0000-0002-1808-8843
Roxanna J FloresTaub Institute for Research on Alzheimer's Disease and the Aging Brain.
Dayanara RosadoTaub Institute for Research on Alzheimer's Disease and the Aging Brain.
Carolyn QianTaub Institute for Research on Alzheimer's Disease and the Aging Brain.
Raquel CaboTaub Institute for Research on Alzheimer's Disease and the Aging Brain.
Josina HabeggerTaub Institute for Research on Alzheimer's Disease and the Aging Brain.
Karmen LouieTaub Institute for Research on Alzheimer's Disease and the Aging Brain.
Elizabeth AlloccoTaub Institute for Research on Alzheimer's Disease and the Aging Brain.ORCID 0000-0001-6589-615X
Adam M BrickmanTaub Institute for Research on Alzheimer's Disease and the Aging Brain.
Jennifer J ManlyTaub Institute for Research on Alzheimer's Disease and the Aging Brain.
Columbia University · US

Funding

Genetic Epidemiology of Cerebrovascular Factors in Alzheimer's DiseaseRF1AG054023 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P · 2016 to 2018
$8.9M
Genetic Epidemiology of Alzheimer's Disease in African AmericansR01AG028786 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MANLY, JENNIFER JAIE · 2007 to 2011
$7.3M
National Institutes of Health; National Institute on AgingNIA NIH HHS R01 AG028786NIA NIH HHS RF1 AG054023
6 · The paper itself

Abstract

objectiveAccurate identification of the earliest cognitive changes associated with Alzheimer's disease (AD) is critically needed. Item-level information within tests of category fluency, such as lexical frequency, harbors valuable information about the integrity of semantic networks affected early in AD. To determine the potential of lexical frequency as a cognitive marker of AD risk, we investigated whether lexical frequency of animal fluency output differentiated

methodWe analyzed animal fluency performance using mean number of items and mean lexical frequency among 230 cognitively normal African Americans with and without the

resultsLexical frequency was higher in

conclusionOur results suggest that psycholinguistic features may hold value as a cognitive biomarker for identifying people at high risk of AD. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Indexed as

HeterozygoteAgedAged, 80 and overAlzheimer DiseaseApolipoprotein E4Cross-Sectional StudiesEarly DiagnosisFemaleGenotypeHumansMaleMiddle AgedPsycholinguisticsSpeechApolipoprotein E4

Identifiers

PMID30489116
PMCPMC6466625
OpenAlexW2902756463

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.