Evidence map›Paper›PMID 30489083›Full record

ArticleJournal of proteome research2019

Site-Specific K63 Ubiquitinomics Provides Insights into Translation Regulation under Stress.

Songhee Back, Andrew W Gorman, Christine Vogel, Gustavo M Silva

Open access · greenAbstract read
In one paragraph

Article in Journal of proteome research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
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  4. Review
  5. Covalent inhibition ofiScience · 2025
    Article
  6. Ribosome-associated proteins: unwRAPping ribosome heterogeneity in the twenty-first century.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Songhee BackCenter for Genomics and Systems Biology , New York University , 12 Waverly Place , New York , New York 10003 , United States.
Andrew W GormanDepartment of Biology , Duke University , 130 Science Drive , Durham , North Carolina 27708 , United States.
Christine VogelCenter for Genomics and Systems Biology , New York University , 12 Waverly Place , New York , New York 10003 , United States.
Gustavo M SilvaDepartment of Biology , Duke University , 130 Science Drive , Durham , North Carolina 27708 , United States.ORCID 0000-0001-9476-069X
Duke University · USNew York University · US

Funding

Next generation gene expression analysisR35GM127089 · NIGMS · NEW YORK UNIVERSITY · PI Christine Vogel · 2018 to 2026
$4.0M
Robust statistical approaches for decoding protein and mRNA expression regulationR01GM113237 · NIGMS · NEW YORK UNIVERSITY · PI VOGEL, CHRISTINE · 2014 to 2017
$1.5M
Defining the roles of ubiquitination during the environmental stress responseR00ES025835 · NIEHS · DUKE UNIVERSITY · PI SILVA, GUSTAVO M · 2018 to 2020
$905k
Defining the roles of ubiquitination during the environmental stress responseK99ES025835 · NIEHS · NEW YORK UNIVERSITY · PI SILVA, GUSTAVO M · 2015 to 2016
$205k
NIEHS NIH HHS K99 ES025835NIEHS NIH HHS R00 ES025835NIGMS NIH HHS R01 GM113237NIGMS NIH HHS R35 GM127089
6 · The paper itself

Abstract

During oxidative stress, K63-linked polyubiquitin chains modify a variety of proteins including ribosomes. Knowledge of the precise sites of K63 ubiquitin is key to understand its function during the response to stress. To identify the sites of K63 ubiquitin, we developed a new mass spectrometry based method that quantified >1100 K63 ubiquitination sites in yeast that responded to oxidative stress induced by H

Indexed as

Oxidative StressUbiquitinationBinding SitesFungal ProteinsHydrogen PeroxideProtein BiosynthesisProtein Processing, Post-TranslationalProteomicsRibosomesUbiquitinYeastsFungal ProteinsHydrogen PeroxideUbiquitinK63 ubiquitinoxidative stressproteomicsribosometranslational control

Identifiers

PMID30489083
PMCPMC6465141
OpenAlexW2903508759

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.