Evidence map›Paper›PMID 30488737›Full record

ArticleCell transplantation2019

Progression in Vascular Cognitive Impairment: Pathogenesis, Neuroimaging Evaluation, and Treatment.

Xin Zhang, Jiabin Su, Chao Gao, Wei Ni, Xinjie Gao, Yuxin Li, Jun Zhang, Yu Lei, Yuxiang Gu

Open access · goldAbstract read
In one paragraph

Article in Cell transplantation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  17. Vascular Cognitive Impairment (VCI).Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xin Zhang1 Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Jiabin Su1 Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Chao Gao1 Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Wei Ni1 Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Xinjie Gao1 Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Yuxin Li2 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
Jun Zhang2 Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
Yu Lei1 Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Yuxiang Gu1 Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
Huashan Hospital · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular cognitive impairment (VCI) defines an entire spectrum of neurologic disorders from mild cognitive impairment to dementia caused by cerebral vascular disease. The pathogenesis of VCI includes ischemic factors (e.g., large vessel occlusion and small vessel dysfunction); hemorrhagic factors (e.g., intracerebral hemorrhage and subarachnoid hemorrhage); and other factors (combined with Alzheimer's disease). Clinical evaluations of VCI mainly refer to neuropsychological testing and imaging assessments, including structural and functional neuroimaging, with different advantages. At present, the main treatment for VCI focuses on neurological protection, cerebral blood flow reconstruction, and neurological rehabilitation, such as pharmacological treatment, revascularization, and cognitive training. In this review, we discuss the pathogenesis, neuroimaging evaluation, and treatment of VCI.

Indexed as

Cerebrovascular DisordersCognitive DysfunctionDementia, VascularDisease ProgressionHumansNeuroimagingNeuropsychological Testsneuroimagingpathogenesisprogressiontreatmentvascular cognitive impairment

Identifiers

PMID30488737
PMCPMC6322135
OpenAlexW2903521492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.