Evidence map›Paper›PMID 30488361›Full record

ReviewJournal of urban health : bulletin of the New York Academy of Medicine2019

Environmental Exposures, the Epigenome, and African American Women's Health.

Joyce E Ohm

Abstract readReview
In one paragraph

Review in Journal of urban health : bulletin of the New York Academy of Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Epigenetics, Resilience, Protective Factors and Factors Promoting Positive Outcomes: A Scoping Review.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2025
    Article
  3. Social Determinants of Cancer Disparities.Annals of surgical oncology · 2023
    Review
  4. Article
  5. Review
  6. Article
  7. Health Equity Among Black Women in the United States.Journal of women's health (2002) · 2021
    Article
  8. Prediagnostic Allostatic Load as a Predictor of Poorly Differentiated and Larger Sized Breast Cancers among Black Women in the Women's Circle of Health Follow-Up Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Joyce E OhmDepartment of Genetics and Genomics, Roswell Park Comprehensive Cancer Center, CGP-L2, Elm and Carlton Streets, Buffalo, NY, 14263, USA. Joyce.ohm@roswellpark.org.ORCID 0000-0002-7390-8701

Funding

Environmental toxins and stem cell epigenetic remodelingR01ES022030 · NIEHS · UNIVERSITY OF NORTH DAKOTA · PI OHM, JOYCE ELLEN · 2012 to 2016
$1.6M
NIEHS NIH HHS R01 ES022030
6 · The paper itself

Abstract

Stress is a common feature of modern life, but both the extent of exposure to stressors and the downstream effects of these stress exposures can vary considerably among individuals, communities, and populations. When individuals are exposed to repeated or chronic stress, wear and tear on the body can accumulate and manifest in many ways. The term "allostatic load" represents the physiological consequences of repeated or chronic exposure to environmental stressors and is linked to fluctuating and/or heightened neural or neuroendocrine responses. African American women are one population subgroup that has been identified as potentially having both an elevated allostatic load and an enhanced resilience to external factors. One mechanism by which environmental stressors may impact human health is via epigenetic remodeling of the genome. This review will focus on what is known about how different types of environmental stressors may affect the epigenome and explore links between epigenetic reprogramming and altered allostatic load and resilience as it pertains to African American women's health.

Indexed as

AllostasisEpigenomeAdultAgedAged, 80 and overBlack or African AmericanEnvironmental ExposureFemaleHumansMiddle AgedStress, PsychologicalUnited StatesWomen's HealthAllostatic loadEpigeneticsStress

Identifiers

PMID30488361
PMCPMC6430284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.