ArticleSocial psychiatry and psychiatric epidemiology2019
A comparison of neurocognition and functioning in first episode psychosis populations: do research samples reflect the real world?
Article in Social psychiatry and psychiatric epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02069925 (STEP-ED), which is not on this map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
STEP-ED: Reducing Duration of Untreated Psychosis and Its Impact in the U.S.
Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Increasing participation of people with thought disorder in clinical research.European psychiatry : the journal of the Association of European Psychiatrists · 2026Review
- Cultural variables influence performance on the MATRICS Consensus Cognitive Battery among people at clinical high risk for psychosis.Schizophrenia research · 2025Article
- Patterns of Impaired Neurocognitive Performance on the Global Neuropsychological Assessment, and Their Brain Structural Correlates in Recent-onset and Chronic Schizophrenia.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023Article
- Prevalence, profile and associations of cognitive impairment in Ugandan first-episode psychosis patients.Schizophrenia research. Cognition · 2022Article
- Rates and Predictors of Disengagement and Strength of Engagement for People With a First Episode of Psychosis Using Early Intervention Services: A Systematic Review of Predictors and Meta-analysis of Disengagement Rates.Schizophrenia bulletin open · 2022Article
- Co-development of a Best Practice Checklist for Mental Health Data Science: A Delphi Study.Frontiers in psychiatry · 2021Article
- How well do hoarding research samples represent cases that rise to community attention?Behaviour research and therapy · 2020Article
- Return to College After a First Episode of Psychosis.Schizophrenia bulletin open · 2020Article
- Early intervention in psychiatry: scotomas, representativeness, and the lens of clinical populations.Social psychiatry and psychiatric epidemiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 3 institutions in 1 country.
Funding
Abstract
purposeThe current study evaluates the demographic, clinical, and neurocognitive characteristics of a recruited FEP research sample, a research control group, and a FEP clinic sample that were assessed and treated within the same center and time period.
methodsThis study utilized data collected through an observational study and a retrospective chart review. Samples were ascertained in the Longitudinal Assessment and Monitoring of Clinical Status and Brain Function in Adolescents and Adults study and the Prevention and Recovery in Early Psychosis clinic. FEP clinic patients (n = 77), FEP research participants (n = 44), and age-matched controls (n = 38) were assessed using the MATRICS consensus cognitive battery and global functioning social and role scales. Between-group differences were assessed via one-way ANOVA and Chi-square analyses.
resultsNo significant differences were observed between groups with regard to age and gender. The FEP research sample had a higher proportion of white participants, better social and role functioning, and better neurocognitive performance when compared with the FEP clinical population. The clinic sample also had more diagnostic variability and higher prevalence of substance use disorders relative to the FEP research sample.
conclusionsResearchers should be aware of how study design and recruitment practices may impact the representativeness of samples, with particular concern for equal representation of racial minorities and patients with more severe illness. Studies should be designed to minimize burden to promote a wider range of participation.
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