Evidence map›Paper›PMID 30487983›Full record

ArticleOpen heart

Disability-free survival after coronary artery bypass grafting in women and men with heart failure.

Louise Y Sun, Jack V Tu, Douglas S Lee, Rob S Beanlands, Marc Ruel, Peter C Austin, Anan Bader Eddeen, Peter P Liu

Open access · goldAbstract read
In one paragraph

Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Time-varying comparative effectiveness of surgical or percutaneous revascularization on patient-centred outcomes.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
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  6. Priority of the basic and instrumental activities of daily living in older patients with cancer prescribed rehabilitation: a cross-sectional survey.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  7. Predictors and clinical outcomes of post-coronary artery bypass grafting cerebrovascular strokes.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Derivation and validation of a clinical model to predict death or cardiac hospitalizations while on the cardiac surgery waitlist.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Multidimensional Approach to Frailty.Frontiers in psychology · 2020
    Review
  17. Older patients with cardiovascular disease: A new frontier for nuclear cardiology?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  18. Article
  19. Review
  20. Impact and Implications of Neurocognitive Dysfunction in the Management of Ischemic Heart Failure.Journal of the Society for Cardiovascular Angiography & Interventions
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Louise Y SunDivision of Cardiac Anesthesiology, Department of Anesthesiology and Pain Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.ORCID 0000-0003-3381-3115
Jack V TuCardiovascular Research Program, Institute for Clinical Evaluative Sciences, Ontario, Canada.
Douglas S LeeCardiovascular Research Program, Institute for Clinical Evaluative Sciences, Ontario, Canada.
Rob S BeanlandsDivision of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Marc RuelDivision of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Peter C AustinCardiovascular Research Program, Institute for Clinical Evaluative Sciences, Ontario, Canada.
Anan Bader EddeenCardiovascular Research Program, Institute for Clinical Evaluative Sciences, Ontario, Canada.
Peter P LiuDivision of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
University of Ottawa · CAInstitute for Clinical Evaluative Sciences · CASunnybrook Health Science Centre · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Heart failure (HF) impairs survival post coronary artery bypass grafting (CABG), but little is known about the postoperative quality of life (QoL) in patients with HF. We derived a patient-centred QoL surrogate and assessed the impact of different HF subtypes on this surrogate in the year post-CABG. Methods: We surveyed 3112 cardiovascular patients to derive a patient-centred disability outcome and studied this outcome in a population-based cohort. We defined preserved ejection fraction as ≥50% and reduced ejection fraction as <50%. The primary outcome was disability, defined according to compiled patient-derived values. The secondary outcomes consisted of each individual component of disability, and death. The incidence of disability was calculated using cumulative incidence functions, with death as a competing risk. We identified predictors of disability using cause-specific hazard models. Results: Patient-derived disability outcome consisted of stroke, nursing home admission and recurrent hospitalisations. When applied to 40 083 CABG patients (20.6% women), the incidence of disability was 5.4% while the incidence of death was 3.7% in the year post-CABG. Female sex was associated with an adjusted HR of 1.25 (95% CI 1.13 to 1.37) for disability. Women with HF with preserved ejection fraction had an adjusted HR of 1.73 (95% CI 1.52 to 1.98) for disability. Conclusions: Disability was a more frequent complication than death in the year post-CABG. Women experienced higher burden of disability than men, and female sex and the presence of HF were important disability risk factors. Efforts should be dedicated to disability risk prediction to enable patient-centred operative decision-making and to developing sex-specific treatment strategies to improve outcomes.

Indexed as

coronary artery bypass graftingdisabilityheart failurePatient-centered outcomesquality of lifesurvival

Identifiers

PMID30487983
PMCPMC6242014
OpenAlexW2899880572

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.