Evidence map›Paper›PMID 30487646›Full record

SynthesisProstate cancer and prostatic diseases2019

Role of multiparametric magnetic resonance imaging for patients under active surveillance for prostate cancer: a systematic review with diagnostic meta-analysis.

Francesco Cantiello, Giorgio Ivan Russo, Sascha Kaufmann, Giovanni Cacciamani, Fabio Crocerossa, Matteo Ferro, Ottavio De Cobelli, Walter Artibani, Sebastiano Cimino, Giuseppe Morgia and 6 more

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Prostate cancer and prostatic diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. [Active surveillance in prostate cancer].Der Urologe. Ausg. A · 2019
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Francesco CantielloDepartment of Urology, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Giorgio Ivan RussoUrology Section, Department of Surgery, University of Catania, Catania, Italy. giorgioivan1987@gmail.com.
Sascha KaufmannDepartment of Urology, Eberhard Karls University of Tuebingen, Tuebingen, Germany.
Giovanni CacciamaniDepartment of Urology, University of Verona, Verona, Italy.
Fabio CrocerossaDepartment of Urology, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Matteo FerroDepartment of Urology, European Institute of Oncology, Milan, Italy.
Ottavio De CobelliDepartment of Urology, European Institute of Oncology, Milan, Italy.
Walter ArtibaniDepartment of Urology, Eberhard Karls University of Tuebingen, Tuebingen, Germany.
Sebastiano CiminoUrology Section, Department of Surgery, University of Catania, Catania, Italy.
Giuseppe MorgiaUrology Section, Department of Surgery, University of Catania, Catania, Italy.ORCID http://orcid.org/0000-0002-7224-7577
Rocco DamianoDepartment of Urology, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Konstantin NikolaouDepartment of Urology, Eberhard Karls University of Tuebingen, Tuebingen, Germany.
Nils KrögerDepartment of Urology, Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany.
Arnulf StenzlDiagnostic and Interventional Radiology, Eberhard Karls University of Tuebingen, Tuebingen, Germany.
Jens BedkeDiagnostic and Interventional Radiology, Eberhard Karls University of Tuebingen, Tuebingen, Germany.
Stephan KruckDiagnostic and Interventional Radiology, Eberhard Karls University of Tuebingen, Tuebingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of multiparametric magnetic resonance imaging (mpMRI) in the setting of patients under active surveillance (AS) is promising. In this systematic-review we aimed to analyse the role of mpMRI in patients under AS.

methodsA comprehensive literature research for English-language original and review articles, recently published, was carried out using Medline, Scopus and Web of sciences databases until 30 October 2017. The following MeSH terms were used: 'active surveillance', 'prostate cancer', 'multiparametric magnetic resonance imaging'. A diagnostic meta-analysis was performed for 3.0 T mpMRI in predicting disease re-classification.

resultsIn total, 226 studies were selected after research and after removal of duplicates. After analysis on inclusion criteria, 43 studies were identified as eligible for this systematic review with a total of 6,605 patients. The timing of MRI during follow-up of AS differed from all studies like criteria for inclusion in the AS protocol. Overall, there was a low risk of bias across all studies. The diagnostic meta-analysis for 1.5 tesla showed a sensitivity of 0.60, negative predictive value (NPV) of 0.75 and a hierarchical summary receiving operating curve (HSROC) of 0.74 while for 3.0 tesla mpMRI a sensitivity of 0.81, a NPV of 0.78 and a HSROC of 0.83.

conclusionsOverall, the available evidence suggests that both 1.5 or 3.0 Tesla mpMRI are a valid tool to monitor progression during AS follow-up, showing good accuracy capabilities in detecting PCa re-classification. However, the modality to better define what means 'disease progression' on mpMRI must be further evaluated.

Indexed as

Multiparametric Magnetic Resonance ImagingWatchful WaitingAdultAgedBiopsyHumansMaleMiddle AgedNomogramsProstateProstatic NeoplasmsROC Curve

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.