Evidence map›Paper›PMID 30487389›Full record

ArticleToxins2018

New Insights on Moojase, a Thrombin-Like Serine Protease from

Fernanda G Amorim, Danilo L Menaldo, Sante E I Carone, Thiago A Silva, Marco A Sartim, Edwin De Pauw, Loic Quinton, Suely V Sampaio

Abstract read
In one paragraph

Article in Toxins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Crosstalk of Inflammation and Coagulation inInternational journal of molecular sciences · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Surgically-induced brain injury: where are we now?Chinese neurosurgical journal · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fernanda G AmorimLaboratório de Toxinologia, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-903, Brazil. fernandagamorim@gmail.com.ORCID 0000-0003-1453-3185
Danilo L MenaldoLaboratório de Toxinologia, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-903, Brazil. menaldo@fcfrp.usp.br.ORCID 0000-0002-8133-3266
Sante E I CaroneLaboratório de Toxinologia, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-903, Brazil. sante.carone@gmail.com.
Thiago A SilvaLaboratório de Toxinologia, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-903, Brazil. tasribeirao@gmail.com.
Marco A SartimLaboratório de Toxinologia, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-903, Brazil. marcosartim@hotmail.com.
Edwin De PauwLaboratory of Mass Spectrometry, Department of Chemistry, University of Liège, 4000 Liège, Belgium. e.depauw@ulg.ac.be.
Loic QuintonLaboratory of Mass Spectrometry, Department of Chemistry, University of Liège, 4000 Liège, Belgium. loic.quinton@ulg.ac.be.ORCID 0000-0001-8153-9590
Suely V SampaioLaboratório de Toxinologia, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto 14040-903, Brazil. suvilela@usp.br.ORCID 0000-0003-3274-180X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Snake venom serine proteases (SVSPs) are enzymes that are capable of interfering in various parts of the blood coagulation cascade, which makes them interesting candidates for the development of new therapeutic drugs. Herein, we isolated and characterized Moojase, a potent coagulant enzyme from

Indexed as

Reptilian ProteinsSerine ProteasesAdultAnimalsBlood CoagulationBothropsEnzyme StabilityFemaleFibrinogenHumansMalePlatelet AggregationSnake VenomsYoung AdultFibrinogenReptilian ProteinsSerine ProteasesSnake VenomsBothrops moojenicoagulationfibrinogenserine proteasesnake venomthrombin-like enzyme

Identifiers

PMID30487389
PMCPMC6316876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.