Evidence map›Paper›PMID 30487153›Full record

ArticlemSphere2018

Regulation of Epstein-Barr Virus Life Cycle and Cell Proliferation by Histone H3K27 Methyltransferase EZH2 in Akata Cells.

Takaya Ichikawa, Yusuke Okuno, Yoshitaka Sato, Fumi Goshima, Hironori Yoshiyama, Teru Kanda, Hiroshi Kimura, Takayuki Murata

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 31 citations in OpenAlex.

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  18. The association between lncRNA H19 and EZH2 expression in patients with EBV-positive laryngeal carcinoma.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Takaya IchikawaDepartment of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yusuke OkunoCenter for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan.
Yoshitaka SatoDepartment of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID 0000-0002-8541-6413
Fumi GoshimaDepartment of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hironori YoshiyamaDepartment of Microbiology, Shimane University Faculty of Medicine, Izumo, Japan.
Teru KandaDivision of Microbiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Hiroshi KimuraDepartment of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID 0000-0001-8063-5660
Takayuki MurataDepartment of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan tmurata@fujita-hu.ac.jp.
Nagoya University · JPFujita Health University · JPNagoya University Hospital · JPShimane University · JPTohoku Medical and Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigenetic modifications play a pivotal role in the expression of the genes of Epstein-Barr virus (EBV). We found that

Indexed as

Cell ProliferationGene Expression Regulation, ViralHost-Pathogen InteractionsVirus ReplicationCell LineEnhancer of Zeste Homolog 2 ProteinEpigenesis, GeneticGene DeletionGene Knockout TechniquesHerpesvirus 4, HumanHumansEnhancer of Zeste Homolog 2 ProteinEZH2 protein, humanEBVEZH2histone methylation

Identifiers

PMID30487153
PMCPMC6262262
OpenAlexW2903012631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.