Evidence map›Paper›PMID 30487069›Full record

ReviewSeminars in perinatology2018

Genomics, microbiomics, proteomics, and metabolomics in bronchopulmonary dysplasia.

Charitharth Vivek Lal, Vineet Bhandari, Namasivayam Ambalavanan

Open access · hybridAbstract readReview
In one paragraph

Review in Seminars in perinatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 57 citations in OpenAlex.

  1. Trial
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  19. Bronchopulmonary Dysplasia: Then, Now, and Next.Pediatric allergy, immunology, and pulmonology · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Charitharth Vivek LalDivision of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Women and Infants Center, 176F Suite 9380, 619 South 19th Street, Birmingham, AL 35249-7335, United States. Electronic address: clal@peds.uab.edu.
Vineet BhandariDepartment of Pediatrics, Drexel University, Philadelphia, PA, United States.
Namasivayam AmbalavananDivision of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Women and Infants Center, 176F Suite 9380, 619 South 19th Street, Birmingham, AL 35249-7335, United States.
University of Alabama at Birmingham · USDrexel University · US

Funding

NICHD Cooperative Multicenter Neonatal Research NetworkU10HD034216 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CARLO FONT, WALDEMAR A. · 1996 to 2015
$6.4M
Azithromycin To Prevent BPD In Ureaplasma-Infected PretermsR01HD067126 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI DAVIS, NATALIE LOUISE, TERRIN, MICHAEL L · 2011 to 2019
$4.7M
Alveolar DevMAPU01HL122626 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AMBALAVANAN, NAMASIVAYAM, HAGOOD, JAMES S. · 2014 to 2018
$3.7M
Vitamin A Supplementation and Retinol Metabolism in the Neonatal PeriodR01HD066982 · NICHD · PENNSYLVANIA STATE UNIVERSITY, THE · PI ROSS, A. CATHARINE · 2010 to 2019
$2.9M
Mechanisms of Pulmonary Microbiota-Induced Inflammation and Vascular Dysfunction in Neonatal Lung InjuryK08HL141652 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LAL, CHARITHARTH VIVEK · 2019 to 2023
$838k
NHLBI NIH HHS K08 HL141652NHLBI NIH HHS U01 HL122626NICHD NIH HHS R01 HD066982NICHD NIH HHS R01 HD067126NICHD NIH HHS U10 HD034216
6 · The paper itself

Abstract

Bronchopulmonary Dysplasia (BPD) is a disorder with a multifactorial etiology and highly variable clinical phenotype. Several traditional biomarkers have been identified, but due to the complex disease phenotype, these biomarkers have low predictive accuracy for BPD. In recent years, newer technologies have facilitated the in-depth and unbiased analysis of 'big data' in delineating the diagnosis, pathogenesis, and mechanisms of diseases. Novel systems-biology based 'omic' approaches, including but not limited to genomics, microbiomics, proteomics, and metabolomics may help define the multiple cellular and humoral interactions that regulate normal as well as abnormal lung development and response to injury that are the hallmarks of BPD.

Indexed as

GenomicsMetabolomicsNeonatologyProteomicsBiomarkersBronchopulmonary DysplasiaFemaleHumansInfant, NewbornIntercellular Signaling Peptides and ProteinsLungPredictive Value of TestsPregnancyRespiratory MucosaBiomarkersIntercellular Signaling Peptides and ProteinsBPDGeneticsMetabolomeMicrobiomeProteomeSystems biology

Identifiers

PMID30487069
PMCPMC8862637
OpenAlexW2895089771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.