Evidence map›Paper›PMID 30486918›Full record

ArticleComparative medicine2018

Longitudinal MRI Evaluation of Ischemic Stroke in the Basal Ganglia of a Rhesus Macaque (

Chun-Xia Li, Doty J Kempf, Frank C Tong, Yumei Yan, Zhengfeng Xu, Fawn R Connor-Stroud, Byron D Ford, Leonard L Howell, Xiaodong Zhang

Open access · greenAbstract readCase Reports
In one paragraph

Article in Comparative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. The case for neuregulin-1 as a clinical treatment for stroke.Frontiers in cellular neuroscience · 2024
    Review
  3. Article
  4. Magnetic resonance imaging of the monkey fetal brain in utero.Investigative magnetic resonance imaging · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chun-Xia LiYerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.
Doty J KempfYerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.
Frank C TongDepartments of Radiology and Psychiatry and Behavioral Sciences, School of Medicine, Emory University, Atlanta, Georgia, USA.
Yumei YanYerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.
Zhengfeng XuMorehouse School of Medicine, Atlanta, Georgia, USA.
Fawn R Connor-StroudYerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.
Byron D FordMorehouse School of Medicine, Atlanta, Georgia, USA; University of California-Riverside School of Medicine, Riverside, California, USA.
Leonard L HowellYerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA; University of California-Riverside School of Medicine, Riverside, California, USA.
Xiaodong ZhangYerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA. xzhang8@emory.edu.
Emory University · USMorehouse School of Medicine · USUniversity of California, Riverside · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
YNPRC NHP CLINICAL MEDICINE RESIDENCY PROGRAM - SUPPLEMENTP51RR000165 · NCRR · EMORY UNIVERSITY · PI RENGARAJAN, JYOTHI · 1985 to 2011
$114.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
NCATS NIH HHS UL1 TR000454NCRR NIH HHS P51 RR000165NIH HHS P51 OD011132
6 · The paper itself

Abstract

An adult rhesus macaque developed seizures after the induction of ischemic stroke. Initially, on the day of surgery, a focal ischemic lesion was present exclusively in the right caudate nucleus. By 48 h after stroke induction, the lesion had extended into the putamen, when a seizure was observed. Our report highlights the temporal changes in infarction of unilateral basal ganglia after acute stroke and the accompanying clinical symptoms. This unusual case may provide additional information regarding the involvement of the basal ganglia in seizures, given that prior case reports and studies usually have not described the temporal and spatial evolution of the lesion before clinical symptoms emerge.

Indexed as

Macaca mulattaAnimalsBasal GangliaMagnetic Resonance ImagingMonkey DiseasesSeizuresStroke

Identifiers

PMID30486918
PMCPMC6310199
OpenAlexW2902486931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.