Evidence map›Paper›PMID 30486815›Full record

ReviewBMC pediatrics2018

Rare presentation of an atrial myxoma in an adolescent patient: a case report and literature review.

Eduardo Macias, Elizabeth Nieman, Kentaro Yomogida, Orlando Petrucci, Cylen Javidan, Kevin Baszis, Shafkat Anwar

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in BMC pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Cardiac myxoma: a comprehensive review.Journal of cardiothoracic surgery · 2025
    Review
  6. Article
  7. Review
  8. [Primary cardiac tumors. Left atrial myxoma. Anesthetic management].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Eduardo MaciasDivision of Cardiology, Department of Pediatrics, Washington University School of Medicine in St. Louis, One Children's Place, Campus Box 8116-NWT, St. Louis, MO, 63110, USA. e.macias@wustl.edu.ORCID 0000-0001-9491-9437
Elizabeth NiemanDivision of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Kentaro YomogidaDivision of Rheumatology, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
Orlando PetrucciDivision of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Cylen JavidanMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Kevin BaszisDivision of Rheumatology, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
Shafkat AnwarDivision of Cardiology, Department of Pediatrics, Washington University School of Medicine in St. Louis, One Children's Place, Campus Box 8116-NWT, St. Louis, MO, 63110, USA.
Washington University in St. Louis · USMallinckrodt (United States) · USSt. Louis Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac tumors are uncommon in the pediatric population. When present, cardiac manifestations stem from the tumor causing inflow or outflow obstruction. While common in adults, cardiac myxomas presenting with generalized systemic illness or peripheral emboli especially with no cardiac or neurological symptoms are rare in children. CASE PRESENTATION: We report a case of a previously healthy adolescent girl who presented with a 6-month history of constitutional symptoms and a purpuric rash with no cardiac or neurologic symptoms, found to have a cardiac myxoma.

conclusionsA vasculopathic rash in the setting of atrial myxomas has been shown be a precursor to significant morbidity and mortality. Due to the rarity of this entity, the time elapsed from onset of non-cardiac symptoms until diagnosis of a myxoma is usually prolonged with interval development of irreversible neurological sequelae and death reported in the literature. Therefore, we highlight the importance of including cardiac myxomas and paraneoplastic vasculitis early in the differential diagnosis for patients presenting with a purpuric rash and systemic symptoms.

Indexed as

AdolescentDelayed DiagnosisDiagnosis, DifferentialEchocardiographyExanthemaFatigueFemaleFeverHeart AtriaHeart NeoplasmsHumansMagnetic Resonance ImagingMyxomaPainPurpuraEmbolic phenomenaMyxomaNeurological sequelaeParaneoplastic vasculitisPurpuric rashSystemic symptoms

Identifiers

PMID30486815
PMCPMC6263045
OpenAlexW2902378052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.