Evidence map›Paper›PMID 30486789›Full record

Observational studyBMC cardiovascular disorders2018

Association between the reported intensity of an acute symptom at first prehospital assessment and the subsequent outcome: a study on patients with acute chest pain and presumed acute coronary syndrome.

Mats Holmberg, Henrik Andersson, Karin Winge, Camilla Lundberg, Thomas Karlsson, Johan Herlitz, Birgitta Wireklint Sundström

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00792181 (Intervention Study to Relieve Pain and Anxiety in Acute Myocardial Disease Focusing on Treatment With Benzodiazepines), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00792181 phase1completednot on this map

Intervention Study to Relieve Pain and Anxiety in Acute Myocardial Disease Focusing on Treatment With Benzodiazepines(Midazolam)and the Importance of a Caring Relation.

TypeinterventionalSponsorSahlgrenska University HospitalRan2008Enrolled2,800ConditionsAcute Myocardial Infarction, PainArmsMidazolam, Course intervention - a professional development course for caregivers.
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Towards definitions of time-sensitive conditions in prehospital care.Scandinavian journal of trauma, resuscitation and emergency medicine · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Mats HolmbergDepartment of Ambulance Service, Sörmland County Council, Eskilstuna, Sweden. mats.holmberg@dll.se.ORCID 0000-0003-1878-0992
Henrik AnderssonPreHospen - Centre for Prehospital Research, University of Borås, Borås, Sweden.
Karin WingeAmbulance Department, South Älvsborgs Hospital, Borås, Sweden.
Camilla LundbergAmbulance Department, South Älvsborgs Hospital, Borås, Sweden.
Thomas KarlssonHealth Metrics at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Johan HerlitzPreHospen - Centre for Prehospital Research, University of Borås, Borås, Sweden.
Birgitta Wireklint SundströmPreHospen - Centre for Prehospital Research, University of Borås, Borås, Sweden.
University of Borås · SESödra Älvsborg Hospital · SEStockholm County Council · SEUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo decrease the morbidity burden of cardiovascular disease and to avoid the development of potentially preventable complications, early assessment and treatment of acute coronary syndrome (ACS) are important. The aim of this study has therefore been to explore the possible association between patients' estimated intensity of chest pain when first seen by the ambulance crew in suspected ACS, and the subsequent outcome before and after arrival in hospital.

methodsData was collected both prospectively and retrospectively. The inclusion criteria were chest pain raising suspicion of ACS and a reported intensity of pain ≥4 on the visual analogue scale.

resultsAll in all, 1603 patients were included in the study. Increased intensity of chest pain was related to: 1) more heart-related complications before hospital admission; 2) a higher proportion of heart failure, anxiety and chest pain after hospital admission; 3) a higher proportion of acute myocardial infarction and 4) a prolonged hospitalisation. However, there was no significant association with mortality neither in 30 days nor in three years. Adjustment for possible confounders including age, a history of smoking and heart failure showed similar results.

conclusionThe estimated intensity of chest pain reported by the patients on admission by the ambulance team was associated with the risk of complications prior to hospital admission, heart failure, anxiety and chest pain after hospital admission, the final diagnosis and the number of days in hospital.

trial registrationClinicalTrials.gov 151:2008/4564 Identifier: NCT00792181. Registred 17 November 2008 'retrospectively registered'.

Indexed as

Acute Coronary SyndromeAngina PectorisEmergency Medical ServicesPain MeasurementAgedAged, 80 and overAmbulancesAnxietyEarly DiagnosisEmergency Medical TechniciansFemaleHealth StatusHeart FailureHumansLength of StayMaleAcute coronary syndromeAmbulance careAmbulance nurseAssessmentChest painPatients´ experiences

Identifiers

PMID30486789
PMCPMC6260754
OpenAlexW2902834916

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.