Evidence map›Paper›PMID 30486500›Full record

ReviewMaterials (Basel, Switzerland)2018

The A, B and C's of Silicone Breast Implants: Anaplastic Large Cell Lymphoma, Biofilm and Capsular Contracture.

Maria Mempin, Honghua Hu, Durdana Chowdhury, Anand Deva, Karen Vickery

Open access · goldAbstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Toxic Shock Syndrome Caused by Methicillin-resistantPlastic and reconstructive surgery. Global open · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Breast Cancer Hormone Therapy Modulates Breast Implant Capsular Contracture.Plastic and reconstructive surgery. Global open · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maria MempinFaculty of Medicine and Health Sciences, Macquarie University, Macquarie Park, NSW, 2109, Australia. maria.mempin@mq.edu.au.
Honghua HuFaculty of Medicine and Health Sciences, Macquarie University, Macquarie Park, NSW, 2109, Australia. helen.hu@mq.edu.au.
Durdana ChowdhuryFaculty of Medicine and Health Sciences, Macquarie University, Macquarie Park, NSW, 2109, Australia. Durdana.chowdhury@hdr.mq.edu.au.
Anand DevaFaculty of Medicine and Health Sciences, Macquarie University, Macquarie Park, NSW, 2109, Australia. anand.deva@mq.edu.au.
Karen VickeryFaculty of Medicine and Health Sciences, Macquarie University, Macquarie Park, NSW, 2109, Australia. karen.vickery@mq.edu.au.ORCID 0000-0003-0998-1370
Macquarie University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast implantation either for cosmetic or reconstructive e purposes is one of the most common procedures performed in plastic surgery. Biofilm infection is hypothesised to be involved in the development of both capsular contracture and anaplastic large cell lymphoma (ALCL). Capsular contracture is one of the principal reasons for breast revision surgery and is characterised by the tightening and hardening of the capsule surrounding the implant, and ALCL is an indolent lymphoma found only in women with textured implants. We describe the types of breast implants available with regard to their surface characteristics of surface area and roughness and how this might contribute to capsular contracture and/or biofilm formation. The pathogenesis of capsular contracture is thought to be due to biofilm formation on the implant, which results in on-going inflammation. We describe the current research into breast implant associated ALCL and how implant properties may affect its pathogenesis, with ALCL only occurring in women with textured implants.

Indexed as

anaplastic large cell lymphomaBIA-ALCLbiofilmbreast implanttextured: capsular contracture

Identifiers

PMID30486500
PMCPMC6316940
OpenAlexW2903192841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.