Evidence map›Paper›PMID 30486489›Full record

ReviewAntioxidants (Basel, Switzerland)2018

Piecing Together How Peroxiredoxins Maintain Genomic Stability.

James D West, Trevor J Roston, Joseph B David, Kristin M Allan, Matthew A Loberg

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Peroxiredoxins in Cancer and Response to Radiation Therapies.Antioxidants (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

James D WestBiochemistry & Molecular Biology Program, Departments of Biology and Chemistry, The College of Wooster, Wooster, OH 44691, USA. jwest@wooster.edu.ORCID 0000-0003-0892-5254
Trevor J RostonBiochemistry & Molecular Biology Program, Departments of Biology and Chemistry, The College of Wooster, Wooster, OH 44691, USA. roston1@live.marshall.edu.
Joseph B DavidBiochemistry & Molecular Biology Program, Departments of Biology and Chemistry, The College of Wooster, Wooster, OH 44691, USA. jdavid15@wooster.edu.
Kristin M AllanBiochemistry & Molecular Biology Program, Departments of Biology and Chemistry, The College of Wooster, Wooster, OH 44691, USA. kallan16@wooster.edu.
Matthew A LobergBiochemistry & Molecular Biology Program, Departments of Biology and Chemistry, The College of Wooster, Wooster, OH 44691, USA. mloberg16@wooster.edu.
College of Wooster · US

Funding

The Mindlin Foundation Awards MF15-UMR06 and MF16-US03
6 · The paper itself

Abstract

Peroxiredoxins, a highly conserved family of thiol oxidoreductases, play a key role in oxidant detoxification by partnering with the thioredoxin system to protect against oxidative stress. In addition to their peroxidase activity, certain types of peroxiredoxins possess other biochemical activities, including assistance in preventing protein aggregation upon exposure to high levels of oxidants (molecular chaperone activity), and the transduction of redox signals to downstream proteins (redox switch activity). Mice lacking the peroxiredoxin Prdx1 exhibit an increased incidence of tumor formation, whereas baker's yeast (

Indexed as

genomic instabilitymutatoroxidative stressperoxiredoxinredox switchribonucleotide reductasesulfiredoxinthiol peroxidasethioredoxin

Identifiers

PMID30486489
PMCPMC6316004
OpenAlexW2902773285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.