Evidence map›Paper›PMID 30486406›Full record

ArticleAntioxidants (Basel, Switzerland)2018

Analysis of Protein Oxidative Modifications in Follicular Fluid from Fertile Women: Natural Versus Stimulated Cycles.

Irantzu Pérez-Ruiz, Susana Meijide, María-Luisa Hérnandez, Rosaura Navarro, Zaloa Larreategui, Marcos Ferrando, María-Begoña Ruiz-Larrea, José-Ignacio Ruiz-Sanz

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Irantzu Pérez-RuizFree Radicals and Oxidative Stress (FROS) research group of the Department of Physiology, Medicine and Nursing School, University of the Basque Country UPV/EHU, 48940 Leioa, Spain. irantzu.perez@ehu.eus.
Susana MeijideFree Radicals and Oxidative Stress (FROS) research group of the Department of Physiology, Medicine and Nursing School, University of the Basque Country UPV/EHU, 48940 Leioa, Spain. sumeijide@gmail.com.
María-Luisa HérnandezFree Radicals and Oxidative Stress (FROS) research group of the Department of Physiology, Medicine and Nursing School, University of the Basque Country UPV/EHU, 48940 Leioa, Spain. luisa.hernandez@ehu.eus.
Rosaura NavarroFree Radicals and Oxidative Stress (FROS) research group of the Department of Physiology, Medicine and Nursing School, University of the Basque Country UPV/EHU, 48940 Leioa, Spain. rosaura.navarro@ehu.eus.
Zaloa LarreateguiValencian Institute of Infertility (IVI-RMA)-Bilbao, 48940 Leioa, Spain. zaloa.larreategui@ivirma.com.
Marcos FerrandoValencian Institute of Infertility (IVI-RMA)-Bilbao, 48940 Leioa, Spain. marcos.ferrando@ivirma.com.
María-Begoña Ruiz-LarreaFree Radicals and Oxidative Stress (FROS) research group of the Department of Physiology, Medicine and Nursing School, University of the Basque Country UPV/EHU, 48940 Leioa, Spain. mbego.ruizlarrea@ehu.eus.
José-Ignacio Ruiz-SanzFree Radicals and Oxidative Stress (FROS) research group of the Department of Physiology, Medicine and Nursing School, University of the Basque Country UPV/EHU, 48940 Leioa, Spain. joseignacio.ruizs@ehu.eus.
University of the Basque Country · ESValencian Infertility Institute · ES

Funding

Basque Government. Department of Economic Development and Competitiveness SPRI. IG-2013 0001214 and IG-2014 0000837Basque Government, Department of Education, Universities and Research. IT687-13University of the Basque Country UPV/EHU. GIU16/62
6 · The paper itself

Abstract

Oxidative stress is associated with obstetric complications during ovarian hyperstimulation in women undergoing in vitro fertilization. The follicular fluid contains high levels of proteins, which are the main targets of free radicals. The aim of this work was to determine specific biomarkers of non-enzymatic oxidative modifications of proteins from follicular fluid in vivo, and the effect of ovarian stimulation with gonadotropins on these biomarkers. For this purpose, 27 fertile women underwent both a natural and a stimulated cycle. The biomarkers, glutamic semialdehyde (GSA), aminoadipic semialdehyde (AASA),

Indexed as

aminoadipic semialdehydeassisted reproductionfemale infertilityfollicular fluidgas chromatography-mass spectrometryglutamic semialdehydeoxidative stress

Identifiers

PMID30486406
PMCPMC6315688
OpenAlexW2902172493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.