Trial reportInternational journal of environmental research and public health2018
Effect of a Toothpaste/Mouthwash Containing
Trial report in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04485520 (Efficacy of the Extract of Carica Papaya as an Inhibitor of Streptococcus Mutans in Students of the Faculty of Dentistry in the Year 2018), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of the Extract of Carica Papaya as an Inhibitor of Streptococcus Mutans in Students of the Faculty of Dentistry in the Year 2018
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Periodontal disease is associated with the risk of cardiovascular disease independent of sex: A meta-analysis.Frontiers in cardiovascular medicine · 2023Pooled it
- Use of over-the-counter mouthwashes as an additional measure in individual oral prophylaxis on adults with plaque-induced gingivitis: a double-blind, parallel, randomized controlled trial.BMC oral health · 2024Trial
- Effect of Polyherbal Toothpaste on Dental Plaque, Gingivitis, and Salivary Antioxidant Levels: A Single-blind Randomized Controlled Trial.International journal of clinical pediatric dentistry · 2025Article
- The Effect of Carica Papaya on Periodontal Disease: A Systematic Review and Meta-Analysis.Advanced biomedical research · 2025Review
- Exploring the therapeutic potential of medicinal plants and their active principles in dental care: A comprehensive review.Heliyon · 2024Review
- Comparative Evaluation of Herbal Versus Non-herbal Dentifrice in Maintaining Oral Health of Young Adults.Cureus · 2024Article
- Exploring the Efficacy of Novel Therapeutic Strategies for Periodontitis: A Literature Review.Life (Basel, Switzerland) · 2024Review
- Innovations in oral hygiene tools: a mini review on recent developments.Frontiers in dental medicine · 2024Review
- Potential Application of the Plant-Derived Essential Oils for Atherosclerosis Treatment: Molecular Mechanisms and Therapeutic Potential.Molecules (Basel, Switzerland) · 2023Review
- The Role of Natural Compounds in Optimizing Contemporary Dental Treatment-Current Status and Future Trends.Journal of functional biomaterials · 2023Review
- Role of Chlorhexidine and Herbal Oral Rinses in Managing Periodontitis.International dental journal · 2023Article
- Revisiting the Therapeutic Effects of Essential Oils on the Oral Microbiome.Pharmacy (Basel, Switzerland) · 2023Review
- A systematic review of medicinal plants and herbal products' effectiveness in oral health and dental cure with health promotion approach.Journal of education and health promotion · 2023Review
- Inhibitory Mechanism of IL-6 Production by Orento in Oral Squamous Cell Carcinoma Cell Line CAL27 Stimulated by Pathogen-Associated Molecular Patterns from PeriodontopathogenicInternational journal of molecular sciences · 2022Article
- Chemical Profile and Biological Activities of Essential Oil fromMolecules (Basel, Switzerland) · 2022Article
- Chemical vs. natural toothpaste: which formulas for which properties? A scoping review.Journal of public health in Africa · 2022Article
- A Fresh Look at Mouthwashes-What Is Inside and What Is It For?International journal of environmental research and public health · 2022Article
- The Current Antimicrobial and Antibiofilm Activities of Synthetic/Herbal/Biomaterials in Dental Application.BioMed research international · 2022Review
- Safety and Efficacy of Medicinal Plants Used to Manufacture Herbal Products with Regulatory Approval in Uganda: A Cross-Sectional Study.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Beneficial Role of Antioxidant Secondary Metabolites from Medicinal Plants in Maintaining Oral Health.Antioxidants (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinical research on herbal-based dentifrice +/- mouth rinse products is very limited compared with the plethora of research on conventional oral care products under normal oral hygiene conditions. The aim of this study was to determine the anti-inflammatory effects of a novel plant
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.