Evidence map›Paper›PMID 30486328›Full record

ArticleNutrients2018

Lipoprotein Profile in Aged Rats Fed Chia Oil- or Hydroxytyrosol-Enriched Pork in High Cholesterol/High Saturated Fat Diets.

Jorge Arturo Santos-López, Alba Garcimartín, Sara Bastida, Mirandeli Bautista-Ávila, María José González-Muñoz, Juana Benedí, Francisco José Sánchez-Muniz

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. SIRT6 regulates SREBP1c-induced glucolipid metabolism in liver and pancreas via the AMPKα-mTORC1 pathway.Laboratory investigation; a journal of technical methods and pathology · 2022
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jorge Arturo Santos-LópezDepartamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain. jorgears@ucm.es.ORCID 0000-0003-4924-0809
Alba GarcimartínDepartamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain. a.garcimartin@ucm.es.
Sara BastidaDepartamento de Nutrición y Ciencia de los Alimentos, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain. sbastida@ucm.es.
Mirandeli Bautista-ÁvilaÁrea Académica de Farmacia, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Ex Hacienda la Concepción s/n, Ctra. Pachuca-Tilcuautla, Hidalgo 42060, Mexico. mirandeli@hotmail.com.
María José González-MuñozDepartamento de Ciencias Biomédicas, Unidad Docente de Toxicología, Facultad de Farmacia, Universidad de Alcalá, Ctra. Madrid-Barcelona km, 33,600, 28805 Alcalá de Henares, Spain. mariajose.gonzalez@uah.es.ORCID 0000-0003-2383-3788
Juana BenedíDepartamento de Farmacología, Farmacognosia y Botánica, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain. jbenedi@ucm.es.
Francisco José Sánchez-MunizDepartamento de Nutrición y Ciencia de los Alimentos, Facultad de Farmacia, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain. frasan@ucm.es.ORCID 0000-0002-2660-5126
Universidad Complutense de Madrid · ESUniversidad Autónoma del Estado de Hidalgo · MXUniversidad de Alcalá · ES

Funding

Ministerio de Economía y Competitividad AGL 2011-29644-C02-02 and AGL 2014-53207-C2-2-R
6 · The paper itself

Abstract

Restructuring pork (RP) by adding new functional ingredients, like Chia oil (one of the richest natural source of α-linolenic acid) or hydroxytyrosol (HxT) (potent antioxidant), both with hypolipidemic activities, is one of the strategies that may help to reduce the potential negative effects of high meat products consumption. The aim of this study was to evaluate the Chia oil- or HxT-enriched-RP effect on the lipoprotein profile of aged rats fed high-fat, high-energy, and cholesterol-enriched diets. RP samples were prepared by mixing lean pork and lard with or without Chia oil (152.2 g/kg fresh matter) or HxT (3.6 g/kg fresh matter). Diets were prepared by mixing a semisynthetic diet with freeze-dried RP. Groups of 1-year male Wistar rats were fed the following experimental diets for 8 weeks: C, control-RP diet; HC, cholesterol-enriched-RP diet; and Chia oil-RP (CHIA) and HxT, Chia oil- or hydroxytyrosol-RP, cholesterol-enriched diet. Plasma lipid, lipoprotein profile, SREBP-1c protein, and low-density lipoproteins (LDL) receptor gene (

Indexed as

Diet, High-FatRed MeatAdipose Tissuealpha-Linolenic AcidAnimalsAntioxidantsCholesterol, DietaryFatty AcidsLipoproteins, LDLLipoproteins, VLDLMalePhenylethyl AlcoholPhospholipidsPlant OilsRats, WistarReceptors, LDL3,4-dihydroxyphenylethanolalpha-Linolenic AcidAntioxidantsCholesterol, DietaryFatty AcidsLipoproteins, LDLLipoproteins, VLDLPhenylethyl AlcoholPhospholipidsPlant OilsReceptors, LDLSrebf1 protein, ratSterol Regulatory Element Binding Protein 1TriglyceridesagingChia oilhydroxytyrosollipoproteinrestructured pork

Identifiers

PMID30486328
PMCPMC6316572
OpenAlexW2902520312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.