Evidence map›Paper›PMID 30485827›Full record

Trial reportDrug and alcohol dependence2019

Alcohol use severity and age moderate the effects of brief interventions in an emergency department randomized controlled trial.

Anne C Fernandez, Rebecca Waller, Maureen A Walton, Erin E Bonar, Rosalinda V Ignacio, Stephen T Chermack, Rebecca M Cunningham, Brenda M Booth, Mark A Ilgen, Kristen L Barry and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  6. Addressing Alcohol Use Disorder in Alcohol-Associated Liver Disease.Clinical and translational gastroenterology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anne C FernandezMichigan Medicine, Addiction Center, Department of Psychiatry, Ann Arbor, MI, 48109, USA. Electronic address: acfernan@med.umich.edu.
Rebecca WallerUniversity of Pennsylvania, Department of Psychology, Philadelphia, PA 19104, USA.
Maureen A WaltonMichigan Medicine, Addiction Center, Department of Psychiatry, Ann Arbor, MI, 48109, USA; Michigan Medicine, Injury Prevention Center, Ann Arbor, MI, 48109, USA.
Erin E BonarMichigan Medicine, Addiction Center, Department of Psychiatry, Ann Arbor, MI, 48109, USA; Michigan Medicine, Injury Prevention Center, Ann Arbor, MI, 48109, USA.
Rosalinda V IgnacioMichigan Medicine, Addiction Center, Department of Psychiatry, Ann Arbor, MI, 48109, USA; Veterans Affairs Ann Arbor Healthcare System, Center for Clinical Management Research, Ann Arbor, MI, 48109, USA.
Stephen T ChermackMichigan Medicine, Addiction Center, Department of Psychiatry, Ann Arbor, MI, 48109, USA; Veterans Affairs Ann Arbor Healthcare System, Mental Health Service, Ann Arbor, MI, 48105, USA.
Rebecca M CunninghamMichigan Medicine, Injury Prevention Center, Ann Arbor, MI, 48109, USA; Michigan Medicine, Department of Emergency Medicine, Ann Arbor, MI, 48109, United States; Hurley Hospital, Flint, MI, 48503, USA; University of Michigan, School of Public Health, Ann Arbor, MI, 48109, USA.
Brenda M BoothUniversity of Arkansas for Medical Sciences, Department of Psychiatry, Little Rock, AR, 72205, USA.
Mark A IlgenMichigan Medicine, Addiction Center, Department of Psychiatry, Ann Arbor, MI, 48109, USA; Veterans Affairs Ann Arbor Healthcare System, Center for Clinical Management Research, Ann Arbor, MI, 48109, USA; Veterans Affairs Ann Arbor Healthcare System, Mental Health Service, Ann Arbor, MI, 48105, USA.
Kristen L BarryMichigan Medicine, Addiction Center, Department of Psychiatry, Ann Arbor, MI, 48109, USA.
Frederic C BlowMichigan Medicine, Addiction Center, Department of Psychiatry, Ann Arbor, MI, 48109, USA; Veterans Affairs Ann Arbor Healthcare System, Center for Clinical Management Research, Ann Arbor, MI, 48109, USA.

Funding

MULTIDISCIPLINARY ALCOHOLISM RESEARCH TRAINING PROGRAMT32AA007477 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Maureen A. Walton · 1990 to 2026
$7.4M
Optimizing Alcohol Brief Interventions in the ED: Computer vs. Clinician DeliveryR01AA018659 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BLOW, FREDERIC C · 2010 to 2014
$3.4M
Integrating Alcohol Screening, Brief Intervention, and Referral to Treatment into Presurgical CareK23AA023869 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FERNANDEZ, ANNE CHRISTIE · 2016 to 2020
$857k
Drug Use and Sexual Risk Behaviors Among Emerging Adults in the ERK23DA036008 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BONAR, ERIN E. · 2013 to 2017
$851k
NIAAA NIH HHS K23 AA023869NIAAA NIH HHS R01 AA018659NIAAA NIH HHS T32 AA007477NIDA NIH HHS K23 DA036008
6 · The paper itself

Abstract

backgroundThe primary aim of this study was to examine the efficacy of two motivational interviewing-based alcohol brief interventions (BIs) among adults presenting to an emergency department (ED). The secondary aim was to evaluate moderators of intervention effects.

methodsParticipants were 750 ED patients reporting recent alcohol misuse. Participants were randomly assigned to: 1) computer-delivered BI (Computer BI), 2) therapist-delivered BI with computer guidance (Therapist BI-CG), or 3) control. The BIs focused on reduction of alcohol use and risk behaviors. The outcome measure was trajectories of alcohol consumption (measured by the AUDIT-C) across baseline, 3-, 6- and 12-month follow-up assessments, analyzed using latent growth curve modeling. Moderation of intervention effect by gender, age, and baseline alcohol use disorder severity was examined.

resultsAcross the full sample (40% males, mean age = 35.8, SD = 12.3), there was an overall reduction in alcohol consumption across 12 months. The main effects of the Therapist and Computer BI were not significant relative to control. Moderation analysis revealed that the impact of Therapist BI-CG, relative to control, was greater on reductions in alcohol consumption in participants with moderate to severe symptoms of alcohol use disorder compared to those with mild symptoms. The effect of the Computer BI on alcohol use, relative to control, was greater among younger participants compared to older participants.

conclusionsWhile no overall effect was shown, ED-based Therapist BI-CG with computer guidance may be effective among patients with moderate-severe drinking patterns, whereas Computer BIs may be more effective for younger participants.

Indexed as

CounselingMotivational InterviewingAdultAlcoholismEmergency Service, HospitalFemaleHumansMaleMiddle AgedRisk-TakingSeverity of Illness IndexTreatment OutcomeYoung AdultAlcohol useBrief interventionComputerized interventionEmergency departmentModerators

Identifiers

PMID30485827
PMCPMC6342480

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.