ArticleBrain and behavior2019
The neurological phenotype of developmental motor patterns during early childhood.
Article in Brain and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic approach to paediatric movement disorders: a clinical practice guide.Developmental medicine and child neurology · 2021Guideline
- Neurological diagnoses in children potentially fulfilling the criteria for developmental coordination disorder.Developmental medicine and child neurology · 2026Article
- REASON CP: a systems-based framework for clinical reasoning to support participation across the lifespan in childhood-onset neurodisability.Frontiers in public health · 2026Review
- Evaluating Primitive Reflexes in Early Childhood as a Potential Biomarker for Developmental Disabilities.Journal of paediatrics and child health · 2025Review
- Cluster analysis of motor coordination and health-related fitness in preschool children: population classification and variable contribution based on principal component analysis.Frontiers in public health · 2025Article
- Pathogenetic Insights into Developmental Coordination Disorder Reveal Substantial Overlap with Movement Disorders.Brain sciences · 2023Article
- Article
- The Polish Version of the Alberta Infant Motor Scale: Cultural Adaptation and Validation.Frontiers in neurology · 2022Article
- Retained Primitive Reflexes and Potential for Intervention in Autistic Spectrum Disorders.Frontiers in neurology · 2022Review
- Is it really a seizure? The challenge of paroxysmal nonepileptic events in young infants.Clinical and experimental pediatrics · 2021Article
- The neurological phenotype of developmental motor patterns during early childhood.Brain and behavior · 2019Article
- The Inverted U: Exploring the Interconnectedness of Movement and Cognitive Function Across the Lifespan.Wiley interdisciplinary reviews. Cognitive scienceReview
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDuring early childhood, typical human motor behavior reveals a gradual transition from automatic motor patterns to acquired motor skills, by the continuous interplay between nature and nurture. During the wiring and shaping of the underlying motor networks, insight into the neurological phenotype of developmental motor patterns is incomplete. In healthy, typically developing children (0-3 years of age), we therefore aimed to investigate the neurological phenotype of developmental motor patterns.
methodsIn 32 healthy, typically developing children (0-3 years), we video-recorded spontaneous motor behavior, general movements (GMs), and standardized motor tasks. We classified the motor patterns by: (a) the traditional neurodevelopmental approach, by Gestalt perception and (b) the classical neurological approach, by the clinical phenotypic determination of movement disorder features. We associated outcomes by Cramer's V.
resultsDevelopmental motor patterns revealed (a) choreatic-like features (≤3 months; associated with fidgety GMs (r = 0.732) and startles (r = 0.687)), (b) myoclonic-like features (≤3 months; associated with fidgety GMs (r = 0.878) and startles (r = 0.808)), (c) dystonic-like features (0-3 years; associated with asymmetrical tonic neck reflex (r = 0.641) and voluntary movements (r = 0.517)), and (d) ataxic-like features (>3 months; associated with voluntary movements (r = 0.928)).
conclusionsIn healthy infants and toddlers (0-3 years), typical developmental motor patterns reveal choreatic-, myoclonic-, dystonic- and ataxic-like features. The transient character of these neurological phenotypes is placed in perspective of the physiological shaping of the underlying motor centers. Neurological phenotypic insight into developmental motor patterns can contribute to adequate discrimination between ontogenetic and initiating pathological movement features and to adequate interpretation of therapeutic interactions.
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