Evidence map›Paper›PMID 30485702›Full record

ArticleInfluenza and other respiratory viruses2019

Serological response to influenza vaccination among adults hospitalized with community-acquired pneumonia.

Caroline Quinn Pratt, Yuwei Zhu, Carlos G Grijalva, Richard G Wunderink, D Mark Courtney, Grant Waterer, Min Z Levine, Stacie Jefferson, Wesley H Self, Derek J Williams and 5 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Influenza and other respiratory viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Caroline Quinn PrattRollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Yuwei ZhuDepartment of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Carlos G GrijalvaDepartment of Health Policy, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Richard G WunderinkDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
D Mark CourtneyDepartment of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Grant WatererDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Min Z LevineCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
Stacie JeffersonCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
Wesley H SelfDepartment of Emergency Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Derek J WilliamsDivision of Hospital Medicine, Monroe Carell Jr. Children's Hospital, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Lynn FinelliCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
Anna M BramleyCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
Kathryn M EdwardsDivision of Infectious Diseases, Monroe Carell Jr. Children's Hospital, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Seema JainCenters for Disease Control and Prevention, Atlanta, Georgia, USA.
Evan J AndersonDepartments of Pediatrics and Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0002-1576-4420
Centers for Disease Control and Prevention · USNorthwestern University · USVanderbilt University · USEmory University · USMonroe Carell Jr. Children's Hospital · US

Funding

Technology CoreU19AI135964 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RICHARD G WUNDERINK · 2018 to 2026
$24.7M
Salivary Cortisol as a Marker of Community-Acquired Pneumonia Severity in AdultsK23GM110469 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SELF, WESLEY H · 2015 to 2018
$683k
NIAID NIH HHS U19 AI135964NIGMS NIH HHS K23 GM110469
6 · The paper itself

Abstract

Ninety-five adults enrolled in the Etiology of Pneumonia in the Community study with negative admission influenza polymerase chain reaction (PCR) tests received influenza vaccination during hospitalization. Acute and convalescent influenza serology was performed. After vaccination, seropositive (≥1:40) hemagglutination antibody titers (HAI) were achieved in 55% to influenza A(H1N1)pdm09, 58% to influenza A(H3N2), 77% to influenza B (Victoria), and 74% to influenza B (Yamagata) viruses. Sixty-six (69%) patients seroconverted (≥4-fold HAI rise) to ≥1 strain. Failure to seroconvert was associated with diabetes, bacterial detection, baseline seropositive titers for influenza B (Yamagata), and influenza vaccination in the previous season.

Indexed as

HospitalizationAdultAgedAntibodies, ViralChicagoCommunity-Acquired InfectionsFemaleHemagglutination Inhibition TestsHumansInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza, HumanInfluenza VaccinesMaleMiddle AgedPneumoniaAntibodies, ViralInfluenza VaccinesRNA, Viral

Identifiers

PMID30485702
PMCPMC6379631
OpenAlexW2903391227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.