ArticleAngewandte Chemie (International ed. in English)2019
Direct Evidence for the Polymeric Nature of Polydopamine.
Article in Angewandte Chemie (International ed. in English), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed.
- Beyond Molecular Determinism: State-Convergent Polymerization as a Functional Design Principle Under Chemical Complexity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Polydopamine-assisted lithium ion loading on titanium alloy synergistically enhances osteogenesis and immunomodulation for bone regeneration: an In Vitro study.BMC oral health · 2026Article
- Allomelanin: A Promising Alternative to Polydopamine for Bioapplications.Journal of functional biomaterials · 2026Review
- Rapid photocontrollable dopamine polymerization for instant adaptive wet adhesion.Nature communications · 2026Article
- Polydopamine-encapsulated modified Pulsatilla decoction: a strategy to enhance ulcerative colitis therapy.Chinese medicine · 2026Article
- Bioinspired bioadhesion: translating nature's adhesive strategies into regenerative medicine.Med-X · 2026Review
- Melanin-Related Materials in Electrochemical Sensors for Monitoring the Environment and Food.Biosensors · 2025Review
- Development and synthesis of DNA-based label-free electrochemical biosensor for detection of Enterocytozoon bieneusi using screen-printed gold electrode.BMC chemistry · 2025Article
- Polydopamine-based Surface Modifications for Tissue Engineering and Biosensing: From Understanding Chemistry to Diverse Applications.JOM (Warrendale, Pa. : 1989) · 2025Article
- Chelation and nanoparticle delivery of monomeric dopamine to increase plant salt stress resistance.Nature communications · 2025Article
- Mussel-inspired remineralizing agent: effects on morphology and permeability of dentin after erosion and abrasion cycling protocol.Clinical oral investigations · 2025Article
- Uptake of Magnetite Nanoparticles on Polydopamine Films Deposited on Gold Surfaces: A Study by AFM and XPS.Nanomaterials (Basel, Switzerland) · 2024Article
- Long-Term Prevention of Biofilm Formation by Polycatechol-Based Supramolecular Assemblies with Low Molecular Weight Polymers on Surfaces.ACS applied materials & interfaces · 2024Article
- Surface Modification Progress for PLGA-Based Cell Scaffolds.Polymers · 2024Review
- A polymer tethering strategy to achieve high metal loading on catalysts for Fenton reactions.Nature communications · 2023Article
- In Vitro/In Vivo Preparation and Evaluation of cRGDyK Peptide-Modified Polydopamine-Bridged Paclitaxel-Loaded Nanoparticles.Pharmaceutics · 2023Article
- A PDA-Functionalized 3D Lung Scaffold Bioplatform to Construct Complicated Breast Tumor Microenvironment for Anticancer Drug Screening and Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Recent progress and future perspectives of polydopamine nanofilms toward functional electrochemical sensors.Analytical and bioanalytical chemistry · 2023Review
- Atomic force and infrared spectroscopic studies on the role of surface charge for the anti-biofouling properties of polydopamine films.Analytical and bioanalytical chemistry · 2023Article
- Preparation of a Mussel-Inspired Supramolecular Polymer Coating Containing Graphene Oxide on Magnesium Alloys with Anti-Corrosion and Self-Healing Properties.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Inspired by the adhesive proteins of mussels, polydopamine (pDA) has emerged as one of the most widely employed materials for surface functionalization. Despite numerous attempts at characterization, little consensus has emerged regarding whether pDA is a covalent polymer or a noncovalent aggregate of low molecular weight species. Here, we employed single-molecule force spectroscopy (SMFS) to characterize pDA films. Retraction of a pDA-coated cantilever from an oxide surface shows the characteristic features of a polymer with contour lengths of up to 200 nm. pDA polymers are generally weakly bound to the surface through much of their contour length, with occasional "sticky" points. Our findings represent the first direct evidence for the polymeric nature of pDA and provide a foundation upon which to better understand and tailor its physicochemical properties.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.