Evidence map›Paper›PMID 30485333›Full record

ArticlePloS one2018

Full reconstruction of large lobula plate tangential cells in Drosophila from a 3D EM dataset.

Kevin M Boergens, Christoph Kapfer, Moritz Helmstaedter, Winfried Denk, Alexander Borst

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. A comprehensive neuroanatomical survey of thebioRxiv : the preprint server for biology · 2023
    Article
  4. Article
  5. Parallel motion vision pathways in the brain of a tropical bee.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2023
    Article
  6. Organization of an Ascending Circuit that Conveys Flight Motor State.bioRxiv : the preprint server for biology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. The diversity of lobula plate tangential cells (LPTCs) in the Drosophila motion vision system.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kevin M BoergensMax-Planck-Institute for Brain Research, Frankfurt, Germany.ORCID 0000-0001-5729-6007
Christoph KapferMax-Planck-Institute of Neurobiology, Martinsried, Germany.
Moritz HelmstaedterMax-Planck-Institute for Brain Research, Frankfurt, Germany.
Winfried DenkMax-Planck-Institute of Neurobiology, Martinsried, Germany.
Alexander BorstMax-Planck-Institute of Neurobiology, Martinsried, Germany.
Max Planck Institute of Neurobiology · DEMax Planck Institute for Brain Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the advent of neurogenetic methods, the neural basis of behavior is presently being analyzed in more and more detail. This is particularly true for visually driven behavior of Drosophila melanogaster where cell-specific driver lines exist that, depending on the combination with appropriate effector genes, allow for targeted recording, silencing and optogenetic stimulation of individual cell-types. Together with detailed connectomic data of large parts of the fly optic lobe, this has recently led to much progress in our understanding of the neural circuits underlying local motion detection. However, how such local information is combined by optic flow sensitive large-field neurons is still incompletely understood. Here, we aim to fill this gap by a dense reconstruction of lobula plate tangential cells of the fly lobula plate. These neurons collect input from many hundreds of local motion-sensing T4/T5 neurons and connect them to descending neurons or central brain areas. We confirm all basic features of HS and VS cells as published previously from light microscopy. In addition, we identified the dorsal and the ventral centrifugal horizontal, dCH and vCH cell, as well as three VSlike cells, including their distinct dendritic and axonal projection area.

Indexed as

Imaging, Three-DimensionalMicroscopy, ElectronAnimalsAxonsDrosophila melanogasterOptic Lobe, NonmammalianSensory Receptor Cells

Identifiers

PMID30485333
PMCPMC6261601
OpenAlexW2902694436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.