ArticleThoracic cancer2019
Lymphovascular invasion as an independent prognostic indicator in radically resected thoracic esophageal squamous cell carcinoma.
Article in Thoracic cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 24 citations in OpenAlex.
- Mucosal Versus Submucosal Lymphovascular Invasion in Early Esophageal Cancer.Annals of surgical oncology · 2026Article
- Spatial nodal pattern refines disease-free survival stratification beyond pathological N stage in resected esophageal squamous cell carcinoma.BMC cancer · 2026Article
- Analyses on patterns of lymph node metastasis and its impact on prognosis in thoracic esophageal squamous cell carcinoma treated with neoadjuvant immunochemotherapy versus chemotherapy alone: a single-center, retrospective cohort study.Frontiers in immunology · 2026Article
- Right versus left thoracic approach esophagectomy for patients with neoadjuvant immunochemotherapy.Annals of medicine · 2025Article
- Lymphovascular Invasion is an Independent Negative Prognostic Factor in Esophageal Adenocarcinoma.Annals of surgical oncology · 2024Article
- Machine learning model based on enhanced CT radiomics for the preoperative prediction of lymphovascular invasion in esophageal squamous cell carcinoma.Frontiers in oncology · 2024Article
- Microscopic venous invasion is a predictor of prognosis in patients with esophageal squamous cell carcinoma undergoing ineffective neoadjuvant chemotherapy and surgery.Esophagus : official journal of the Japan Esophageal Society · 2023Article
- Prognostic significance of lymphovascular invasion in patients with pT1b esophageal squamous cell carcinoma.BMC cancer · 2023Article
- Analysis of the influencing factors in the long-term survival of esophageal cancer.Frontiers in oncology · 2023Article
- A radiomics nomogram based on contrast-enhanced CT for preoperative prediction of Lymphovascular invasion in esophageal squamous cell carcinoma.Frontiers in oncology · 2023Article
- The clinicopathological and microrna expression signature associated with lymphovascular invasion in squamous cell carcinoma: A basic descriptive study.Health science reports · 2022Article
- Lymphovascular invasion predicts disease-specific survival in node-negative esophageal squamous cell carcinoma patients after minimally invasive esophagectomy.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022Article
- Computed tomography-based radiomics analysis to predict lymphovascular invasion in esophageal squamous cell carcinoma.The British journal of radiology · 2022Article
- Risk factors of lymph node metastasis or lymphovascular invasion for superficial esophageal squamous cell carcinoma: A practical and effective predictive nomogram based on a cancer hospital data.Frontiers in medicine · 2022Article
- The staging performance of a modified tumor-node-metastasis staging system incorporated with lymphovascular invasion in patients with esophageal squamous cell carcinoma.Frontiers in oncology · 2022Article
- A Nomogram for Predicting Lymphovascular Invasion in Superficial Esophageal Squamous Cell Carcinoma.Frontiers in oncology · 2021Article
- Contrast-Enhanced CT-Based Radiomics Analysis in Predicting Lymphovascular Invasion in Esophageal Squamous Cell Carcinoma.Frontiers in oncology · 2021Article
- Lymphovascular Invasion as a Prognostic Factor in Non-Metastatic Adenocarcinoma of Esophagogastric Junction After Radical Surgery.Cancer management and research · 2020Article
- The prognostic role of angiolymphatic invasion in N0 esophageal carcinoma: a meta-analysis and systematic review.Journal of thoracic disease · 2019Article
- Can Lymphovascular Invasion be Predicted by Preoperative Contrast-Enhanced CT in Esophageal Squamous Cell Carcinoma?Technology in cancer research & treatmentArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prognostic value of lymphovascular invasion (LVI) in esophageal cancer remains controversial. This study investigated the impact of LVI on prognosis in thoracic esophageal squamous cell carcinoma (ESCC).
methodsA total of 1586 patients who underwent radical esophagectomy were selected for the study. Correlations between LVI and clinicopathological features were evaluated by χ
resultsThe presence of LVI was detected in 406 of 1586 (25.6%) patients. LVI frequency was significantly higher in patients with higher pN classifications (P < 0.001). LVI had independent significant prognostic value in ESCC (P < 0.001). In subgroup analyses, the presence of LVI significantly decreased overall survival in pN0, pN2, and pN3 stage patients. The AIC value of the pN staging system modified by LVI was lower than that of the current pN staging system, while the c-index of the modified pN staging system was higher than that of the current pN staging system.
conclusionOur results suggest that LVI is an independent prognostic indicator in radically resected thoracic ESCC. LVI could potentially supplement the pN ESCC staging system. ESCC patients with LVI could be staged at more advanced pN classifications.
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