Evidence map›Paper›PMID 30484952›Full record

ArticleJournal of cellular and molecular medicine2019

One method to establish Epstein-Barr virus-associated NK/T cell lymphoma mouse models.

Weili Xue, Weiming Li, Yufeng Shang, Yanjie Zhang, Xuan Lan, Guannan Wang, Zhaoming Li, Xudong Zhang, Yue Song, Baopeng Wu and 3 more

Erratum issuedAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Corrigendum.Journal of cellular and molecular medicine · 2023
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Weili XueDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0002-1885-3920
Weiming LiDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yufeng ShangDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yanjie ZhangDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xuan LanDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0003-1815-836X
Guannan WangDepartment of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhaoming LiDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xudong ZhangDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yue SongDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Baopeng WuThe Boiler & Pressure Vessel Safety Inspection Institute of Henan Province, Zhengzhou, China.
Meng DongDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xinhua WangDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Mingzhi ZhangDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0001-8428-6090

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel nude mice model of human NK/T cell lymphoma were established by subcutaneously injecting two NK/T cell lymphoma cell lines into the right axillary region of mice and successful passages were completed by injecting cell suspension which was obtained through a 70-μm cell strainer. These mice models and corresponding cell clones have been successfully developed for more than 8 generations. The survival rates of both resuscitation and transplantation in NKYS and YT models were 90% and 70% correspondingly. Pathologically, the tumour cells in all passages of the lymphoma-bearing mice and cell lines obtained from tumours were parallel to initial cell lines. Immunologically, the tumour cells expressed the characteristics of the primary and essential NK/T lymphomas. The novel mice models maintained the essential features of human NK/T cell lymphoma, and they would be ideal tools in vivo for further research of human NK/T cell lymphoma.

Indexed as

Disease Models, AnimalAnimalsCell Line, TumorHerpesvirus 4, HumanHumansKiller Cells, NaturalLymphoma, Extranodal NK-T-CellMiceMice, Nudemethods to establish mouse modelsmouse modelsNK/T cell lymphoma

Identifiers

PMID30484952
PMCPMC6349153

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.