Evidence map›Paper›PMID 30484771›Full record

ArticleeLife2018

Human-specific

Nereo Kalebic, Carlotta Gilardi, Mareike Albert, Takashi Namba, Katherine R Long, Milos Kostic, Barbara Langen, Wieland B Huttner

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 118 citations in OpenAlex.

  1. Review
  2. Influence ofGenome research · 2026
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  10. Influence ofbioRxiv : the preprint server for biology · 2025
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  12. Shaping the Neocortex: Radial Glia and Astrocytes in Development and Evolution.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  13. Article
  14. Reduced Adult Neurogenesis in Humans Results From a Tradeoff Rather Than Direct Negative Selection.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  15. Human-specific gene expansions contribute to brain evolution.bioRxiv : the preprint server for biology · 2025
    Article
  16. Review
  17. The Control of Cortical Folding: Multiple Mechanisms, Multiple Models.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024
    Review
  18. Reconstructing human-specific regulatory functions in model systems.Current opinion in genetics & development · 2024
    Review
  19. Review
  20. Indirect neurogenesis in space and time.Nature reviews. Neuroscience · 2024
    Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nereo KalebicMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID http://orcid.org/0000-0002-8445-2906
Carlotta GilardiMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Mareike AlbertMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID http://orcid.org/0000-0001-9855-9344
Takashi NambaMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Katherine R LongMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID http://orcid.org/0000-0003-0660-2486
Milos KosticMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Barbara LangenMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Wieland B HuttnerMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.ORCID http://orcid.org/0000-0003-4143-7201
Max Planck Institute of Molecular Cell Biology and Genetics · DE

Funding

European Research Council 250197
6 · The paper itself

Abstract

The evolutionary increase in size and complexity of the primate neocortex is thought to underlie the higher cognitive abilities of humans.

Indexed as

AnimalsElectroporationEmbryo, MammalianEpendymoglial CellsFemaleFerretsGene Expression Regulation, DevelopmentalGenes, ReporterGreen Fluorescent ProteinsGTPase-Activating ProteinsHumansLuminescent ProteinsMiceNeocortexNeural Stem CellsNeurogenesisARHGAP11B protein, humanGreen Fluorescent ProteinsGTPase-Activating ProteinsLuminescent ProteinsRed Fluorescent ProteinARHGAP11Bdevelopmental biologyferretneocortex developmentneocortex evolutionneuroscience

Identifiers

PMID30484771
PMCPMC6303107
OpenAlexW2952887780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.