Evidence map›Paper›PMID 30484115›Full record

ArticleInternational journal of computer assisted radiology and surgery2019

Deep-learned placental vessel segmentation for intraoperative video enhancement in fetoscopic surgery.

Praneeth Sadda, Metehan Imamoglu, Michael Dombrowski, Xenophon Papademetris, Mert O Bahtiyar, John Onofrey

Abstract read
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  8. Review
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  13. FetNet: a recurrent convolutional network for occlusion identification in fetoscopic videos.International journal of computer assisted radiology and surgery · 2020
    Article
  14. Artificial Intelligence in Imaging: The Radiologist's Role.Journal of the American College of Radiology : JACR · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Praneeth SaddaYale University School of Medicine, New Haven, USA. praneeth.sadda@yale.edu.ORCID http://orcid.org/0000-0002-3404-9000
Metehan ImamogluYale University School of Medicine, New Haven, USA.
Michael DombrowskiYale University School of Medicine, New Haven, USA.
Xenophon PapademetrisYale University School of Medicine, New Haven, USA.
Mert O BahtiyarYale University School of Medicine, New Haven, USA.
John OnofreyYale University School of Medicine, New Haven, USA.
Yale University · US

Funding

Short Term Research Training: Students in Health Professional SchoolsT35DK104689 · NIDDK · YALE UNIVERSITY · PI LLOYD G CANTLEY, Sarwat I Chaudhry · 2015 to 2026
$2.6M
Foundation for the National Institutes of Health T35DK104689NIDDK NIH HHS T35 DK104689
6 · The paper itself

Abstract

introductionTwin-to-twin transfusion syndrome (TTTS) is a potentially lethal condition that affects pregnancies in which twins share a single placenta. The definitive treatment for TTTS is fetoscopic laser photocoagulation, a procedure in which placental blood vessels are selectively cauterized. Challenges in this procedure include difficulty in quickly identifying placental blood vessels due to the many artifacts in the endoscopic video that the surgeon uses for navigation. We propose using deep-learned segmentations of blood vessels to create masks that can be recombined with the original fetoscopic video frame in such a way that the location of placental blood vessels is discernable at a glance.

methodsIn a process approved by an institutional review board, intraoperative videos were acquired from ten fetoscopic laser photocoagulation surgeries performed at Yale New Haven Hospital. A total of 345 video frames were selected from these videos at regularly spaced time intervals. The video frames were segmented once by an expert human rater (a clinician) and once by a novice, but trained human rater (an undergraduate student). The segmentations were used to train a fully convolutional neural network of 25 layers.

resultsThe neural network was able to produce segmentations with a high similarity to ground truth segmentations produced by an expert human rater (sensitivity = 92.15% ± 10.69%) and produced segmentations that were significantly more accurate than those produced by a novice human rater (sensitivity = 56.87% ± 21.64%; p < 0.01).

conclusionA convolutional neural network can be trained to segment placental blood vessels with near-human accuracy and can exceed the accuracy of novice human raters. Recombining these segmentations with the original fetoscopic video frames can produced enhanced frames in which blood vessels are easily detectable. This has significant implications for aiding fetoscopic surgeons-especially trainees who are not yet at an expert level.

Indexed as

Deep LearningLaser CoagulationFemaleFetofetal TransfusionFetoscopyHumansImage Processing, Computer-AssistedPlacentaPregnancySensitivity and SpecificityVascular Surgical ProceduresConvolutional neural networkDeep learningFetoscopySegmentationTwin-to-twin transfusion syndromeVessels

Identifiers

PMID30484115
PMCPMC6438174
OpenAlexW2901986869

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.