SynthesisNeurocritical care2019
A Systematic Review Assessing the Current State of Automated Pupillometry in the NeuroICU.
Synthesis in Neurocritical care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Outcome pRognostication of Acute Brain Injury With the NeuroloGical Pupil
Percutaneous Neurostimulation for Treatment of Paroxysmal Sympathetic Hyperactivity in Children With Acute Severe Brain Injury
Who cites it
34 citing papers in PubMed, 79 citations in OpenAlex.
- Updating Traumatic Brain Injury Classification for Surgeons: Integrating the CBI-M Framework Into Trauma and Acute Care Practice.World journal of surgery · 2026Review
- The association between neurologic pupillary index (NPi) and functional outcomes in critically ill children.BMC pediatrics · 2025Observational
- SmartPLR: a digital solution for AI-powered smartphone pupillometry.BMC ophthalmology · 2025Article
- Dangerous Alarming Diameter Assessment (DADA Index) in Which the Ratio of Iris Surface/Pupil Surface Size Is More Reliable than Pupil Diameter Measurement in Comatose Patients After Subarachnoid Haemorrhage: An Experimental Rabbit Model.Diagnostics (Basel, Switzerland) · 2025Article
- The Influence of Opioids on Pupil Initial Diameter and Pupillary Dilation Velocity in ICU Patients.Acta anaesthesiologica Scandinavica · 2025Observational
- Clinical Assessment on Days 1-14 for the Characterization of Traumatic Brain Injury: Recommendations from the 2024 NINDS Traumatic Brain Injury Classification and Nomenclature Initiative Clinical/Symptoms Working Group.Journal of neurotrauma · 2025Review
- Quantitative Pupillometry Predicts Neurologic Deterioration in Patients with Large Middle Cerebral Artery Stroke.Annals of neurology · 2025Observational
- Observational
- A point-of-care evaluation after visual loss following paraclinoid aneurysm repair: the role of sonographic and pupillometer assessment.Acute and critical care · 2025Article
- Comparison of automated ultrasound pupillometry assessment vs. infrared pupillary in critically ill patients.Frontiers in medicine · 2025Article
- Article
- Evolving concepts in intracranial pressure monitoring - from traditional monitoring to precision medicine.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- Evaluating optic system compression in sellar tumors: A novel application of quantitative pupillometry.Acta neurochirurgica · 2024Article
- Automated ultrasonographic pupillary assessment: a new neuro-ophthalmological assessment tool.The Journal of international medical research · 2024Observational
- Quantitative Pupillometry for Intracranial Pressure (ICP) Monitoring in Traumatic Brain Injury: A Scoping Review.Neurocritical care · 2024Article
- Machine learning approach for ambient-light-corrected parameters and the Pupil Reactivity (PuRe) score in smartphone-based pupillometry.Frontiers in neurology · 2024Article
- Automated pupillometry and optic nerve sheath diameter ultrasound to define tuberculous meningitis disease severity and prognosis.Journal of the neurological sciences · 2023Article
- Quantitative Pupillometry: Not a Clear Predictor of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage.Neurocritical care · 2023Article
- PupillOmetry for preDIction of DeliriUM in ICU (PODIUM): protocol for a prospective multicentre cohort study.BMJ open · 2023Article
- Dexmedetomidine and Other Analgosedatives Alter Pupil Characteristics in Critically Ill Patients.Critical care explorations · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to assess the current state of automated pupillometry technology and its application in the neurointensive care unit (neuroICU). We performed a literature search using the PubMed, MEDLINE, and EMBASE databases from database inception through a search end date of October 18, 2018, to identify studies reporting on the use of automated pupillometry in the care of critically ill patients with neurological impairment. Two independent reviewers reviewed all titles and abstracts in two filtering phases. Data were extracted independently. One hundred and forty-one articles/abstracts have been published on the use of automated pupillometry in critical care since inception of the PubMed, MEDLINE, and EMBASE databases. We selected and reviewed 22 full-text articles and 8 abstracts, of which 26 were prospective, 2 were retrospective, and 2 were larger case series. Automated pupillometry increased precision, reliability, and reproducibility compared with the manual pupillary examination; detected subtle and early pupillary changes; detected pupillary changes that indicate a rise, or impending rise, in intracranial pressure detected level of analgesia and depth of sedation; served as a prognostic indicator; estimated the clinical severity of aneurysmal subarachnoid hemorrhage; and served as a noninvasive monitor of response to osmotic therapy. At present, no consensus guidelines exist endorsing routine use of automated pupillometry in the neuroICU. However, an increasing quantity of research supports the usefulness of automated pupillometry in this setting. Further large-scale prospective studies are needed before updated consensus guidelines recommending widespread adoption of automated pupillometry are produced.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.