Evidence map›Paper›PMID 30483883›Full record

ArticleWorld journal of surgery2019

Rapid Relief: Thyroidectomy is a Quicker Cure than Radioactive Iodine Ablation (RAI) in Patients with Hyperthyroidism.

James R Davis, Alan P Dackiw, Shelby A Holt, Fiemu E Nwariaku, Sarah C Oltmann

Abstract read
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In one paragraph

Article in World journal of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

James R DavisDivision of Endocrine Surgery, Department of Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., E6.104B, Dallas, TX, 75390-9092, USA.
Alan P DackiwDivision of Endocrine Surgery, Department of Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., E6.104B, Dallas, TX, 75390-9092, USA.
Shelby A HoltDivision of Endocrine Surgery, Department of Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., E6.104B, Dallas, TX, 75390-9092, USA.
Fiemu E NwariakuDivision of Endocrine Surgery, Department of Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., E6.104B, Dallas, TX, 75390-9092, USA.
Sarah C OltmannDivision of Endocrine Surgery, Department of Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., E6.104B, Dallas, TX, 75390-9092, USA. Sarah.oltmann@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTime to hormonal control after definitive management of hyperthyroidism is unknown but may influence patient and physician decision making when choosing between treatment options. The hypothesis is that the euthyroid state is achieved faster after thyroidectomy than RAI ablation.

methodsA retrospective review of all patients undergoing definitive therapy for hyperthyroidism was performed. Outcomes after thyroidectomy were compared to RAI.

resultsOver 3 years, 217 patients underwent definitive therapy for hyperthyroidism at a county hospital: 121 patients received RAI, and 96 patients underwent thyroidectomy. Age was equivalent (p = 0.72). More males underwent RAI (25% vs 15%, p = 0.05). Endocrinologists referred for both treatments equally (p = 0.82). Both treatments were offered after a minimum 1-year trial of medical management (p = 0.15). RAI patients mostly had Graves (93%), versus 73% of thyroidectomy patients (p < 0.001). Thyroidectomy patients more frequently had eye symptoms (35% vs 13%, p < 0.001), compressive symptoms (74% vs 15%, p < 0.001), or were pregnant/nursing (14% vs 0, p < 0.001). While the thyroidectomy patients had a documented discussion of all treatment modalities, 79% of RAI patients did not have a documented discussion regarding the option of surgical management (p < 0.001). Both treatment groups achieved an euthyroid state (71% vs 65%, p = 0.39). Thyroidectomy patients became euthyroid faster [3 months (2-7 months) versus 9 months (4-14 months); p < 0.001].

conclusionsThyroidectomy for hyperthyroidism renders a patient to an euthyroid state faster than RAI. This finding may be important for patients and clinicians considering definitive options for hyperthyroidism.

Indexed as

ThyroidectomyAdultCommunicationFemaleGraves DiseaseHumansIodine RadioisotopesMaleMiddle AgedPatient Education as TopicRetrospective StudiesTime FactorsTriiodothyronineIodine RadioisotopesTriiodothyronine

Identifiers

PMID30483883
OpenAlexW2903104029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.