ArticleAbdominal radiology (New York)2020
Magnetic resonance imaging performed before and after preoperative chemoradiotherapy in rectal cancer: predictive factors of recurrence and prognostic significance of MR-detected extramural venous invasion.
Article in Abdominal radiology (New York), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prognostic value of MRI-detected extramural vascular invasion (mrEMVI) for rectal cancer patients treated with neoadjuvant therapy: a meta-analysis.European radiology · 2021Pooled it
- Navigating pelvic anatomy for exenteration: a clinical guide for radiologists.The British journal of radiology · 2026Review
- Quantitative evaluation for preoperative clinical stage of colorectal cancer using dynamic contrast-enhanced magnetic resonance imaging.World journal of gastrointestinal surgery · 2025Article
- Association of Pelvic Structure Involvement and Tumor Morphology at MRI with Prognosis Following Resection in Locally Recurrent Rectal Cancer.Radiology. Imaging cancer · 2025Observational
- MRI for Rectal Cancer: Updates and Controversies-AJR. American journal of roentgenology · 2025Review
- Prediction of pathological response and lymph node metastasis after neoadjuvant therapy in rectal cancer through tumor and mesorectal MRI radiomic features.Scientific reports · 2024Article
- The Role of Predictive and Prognostic MRI-Based Biomarkers in the Era of Total Neoadjuvant Treatment in Rectal Cancer.Cancers · 2024Review
- Watch & wait - Post neoadjuvant imaging for rectal cancer.Clinical imaging · 2024Review
- Golden-angle radial sparse parallel magnetic resonance imaging of rectal perfusion: utility in the diagnosis of poorly differentiated rectal cancer.Quantitative imaging in medicine and surgery · 2023Article
- Predicting lymphovascular invasion in rectal cancer: evaluating the performance of golden-angle radial sparse parallel MRI for rectal perfusion assessment.Scientific reports · 2023Article
- Watch-and-Wait Approach to Rectal Cancer: The Role of Imaging.Radiology · 2023Review
- Assessing the predictive value of clinical factors to pathological complete response for locally advanced rectal cancer: An analysis of 124 patients.Frontiers in oncology · 2023Article
- The importance of MRI for rectal cancer evaluation.Surgical oncology · 2022Review
- Preoperative prediction of extramural venous invasion in rectal cancer by dynamic contrast-enhanced and diffusion weighted MRI: a preliminary study.BMC medical imaging · 2022Article
- Histopathological, Radiological, and Demographic Factors Predicting the Response to Neoadjuvant Therapy for Rectal Cancer.Journal of gastrointestinal cancer · 2022Article
- Combination of Changes in CEA and CA199 Concentration After Neoadjuvant Chemoradiotherapy Could Predict the Prognosis of Stage II/III Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy Followed by Total Mesorectal Excision.Cancer management and research · 2022Article
- The development and validation of a predictive model for recurrence in rectal cancer based on radiological and clinicopathological data.European radiology · 2021Article
- Prognostic risk factors and survival models for T3 locally advanced rectal cancer: what can we learn from the baseline MRI?European radiology · 2021Article
- Primary and post-chemoradiotherapy MRI detection of extramural venous invasion in rectal cancer: the role of diffusion-weighted imaging.La Radiologia medica · 2020Article
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Abstract
purposeTo evaluate the role of magnetic resonance imaging (MRI) performed before and after neoadjuvant chemoradiotherapy (nCRT) in predicting risk of recurrence in rectal cancer and to investigate the prognostic significance of MR-detected extramural venous invasion (mr-EMVI) and of its regression after nCRT.
methodsDuring 2005-2016, 87 patients with rectal cancer underwent pre- and post-nCRT MRI before surgery. Two radiologists independently reviewed MR examinations retrospectively, assessing T stage, nodal involvement, circumferential resection margin (CRM) status, and mr-EMVI. All four parameters assessed in pre- and post-nCRT MRI were correlated with the risk of recurrence. Correlation with disease-free survival (DFS) was investigated for significant predictive factors in pre-nCRT MRI and for mr-EMVI and its possible regression in post-nCRT MRI.
results15 of 87 patients developed recurrence, with a relapse-rate of 17.2%. Statistical analysis showed a significant correlation between CRM involvement and mr-EMVI assessed in pre-nCRT MRI and the risk of recurrence; 3 years-DFS in patients positive for these two parameters was significantly shorter compared with negatives. In post-nCRT MRI, all four parameters correlated significantly with recurrence: mr-EMVI affected significantly 3 years-DFS and its regression after nCRT correlated with a trend toward improvement of survival outcomes, although not statistically significant.
conclusionsCRM involvement and mr-EMVI assessed in pre-nCRT MRI should be considered early predictive factors of recurrence in rectal cancer. MRI performed after nCRT has a significant value in predicting risk of recurrence: mr-EMVI confirmed to be a poor prognosis predictor and its regression or persistence after nCRT could have influences on treatment and follow-up strategies.
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