Evidence map›Paper›PMID 30483821›Full record

ArticleJournal of molecular medicine (Berlin, Germany)2019

Interleukin-23 receptor signaling mediates cancer dormancy and radioresistance in human esophageal squamous carcinoma cells via the Wnt/Notch pathway.

Yuepeng Zhou, Yuting Su, Haitao Zhu, Xuefeng Wang, Xiaoqin Li, Chunhua Dai, Chengcheng Xu, Tingting Zheng, Chaoming Mao, Deyu Chen

Open access · hybridAbstract read
In one paragraph

Article in Journal of molecular medicine (Berlin, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Study Deciphering the Crucial Involvement of Notch Signaling Pathway in Human Cancers.Endocrine, metabolic & immune disorders drug targets · 2024
    Review
  8. Review
  9. Review
  10. Effect ofArchives of Razi Institute · 2022
    Article
  11. Signaling pathways and their potential therapeutic utility in esophageal squamous cell carcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Review
  12. Review
  13. Review
  14. Fibroblasts in cancer dormancy: foe or friend?Cancer cell international · 2021
    Review
  15. Autophagy and Cancer Dormancy.Frontiers in oncology · 2021
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yuepeng ZhouInstitute of Oncology, Affiliated Hospital of Jiangsu University, Jiefang Road 438, Zhenjiang, 212001, China.
Yuting SuInstitute of Oncology, Affiliated Hospital of Jiangsu University, Jiefang Road 438, Zhenjiang, 212001, China.
Haitao ZhuDepartment of Medical Imaging, Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China.
Xuefeng WangDepartment of Nuclear Medicine, Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China.
Xiaoqin LiInstitute of Oncology, Affiliated Hospital of Jiangsu University, Jiefang Road 438, Zhenjiang, 212001, China.
Chunhua DaiInstitute of Oncology, Affiliated Hospital of Jiangsu University, Jiefang Road 438, Zhenjiang, 212001, China.
Chengcheng XuDepartment of Nuclear Medicine, Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China.
Tingting ZhengDepartment of Nuclear Medicine, Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, China.
Chaoming MaoInstitute of Oncology, Affiliated Hospital of Jiangsu University, Jiefang Road 438, Zhenjiang, 212001, China. jq1001@ujs.edu.cn.
Deyu ChenInstitute of Oncology, Affiliated Hospital of Jiangsu University, Jiefang Road 438, Zhenjiang, 212001, China. cdeyu@hotmail.com.
Affiliated Hospital of Jiangsu University · CNJiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the tumor microenvironment, inflammatory cells and molecules influence almost every process; among them, interleukin-23 (IL-23) is a pro-inflammatory molecule that exhibits pro- or anti-tumor properties, but both activities remain poorly understood. In this study, we investigated the effect of extracellular IL-23 in IL-23 receptor-positive (IL-23R

Indexed as

Signal TransductionWnt Signaling PathwayAnimalsCell Line, TumorEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaFemaleHumansMice, Inbred BALB CMice, NudeReceptors, InterleukinReceptors, NotchIL23R protein, humanReceptors, InterleukinReceptors, NotchBiomarkerInterleukin-23M1 macrophageRadioresistanceWnt/notch

Identifiers

PMID30483821
PMCPMC6348073
OpenAlexW2902470311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.