Evidence map›Paper›PMID 30483696›Full record

ArticleOrganic & biomolecular chemistry2019

An enantioselective synthesis of α-alkylated pyrroles via cooperative isothiourea/palladium catalysis.

W Rush Scaggs, Toya D Scaggs, Thomas N Snaddon

Abstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Total Synthesis of Calyciphylline F.Angewandte Chemie (International ed. in English) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Generation and Reactivity of C(1)-Ammonium Enolates by Using Isothiourea Catalysis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

W Rush ScaggsDepartment of Chemistry, Indiana University, 800 E Kirkwood Ave., Bloomington, IN 47405, USA. tsnaddon@indiana.edu.
Toya D Scaggs
Thomas N Snaddon

Funding

Asymmetric Chemical Synthesis Methods via Cooperative CatalysisR01GM121573 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI SNADDON, THOMAS NEIL · 2016 to 2020
$1.5M
NIGMS NIH HHS R01 GM121573
6 · The paper itself

Abstract

Herein we describe the direct enantioselective Lewis base/Pd catalysed α-allylation of pyrrole acetic acid esters. This provides high isolated yields of highly enantioenriched products and exhibits broad reaction scope with respect to both reaction partners. The products can be readily elaborated in a manner which points towards potential applications in target directed synthesis.

Identifiers

PMID30483696
PMCPMC6499370

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.