Evidence map›Paper›PMID 30483599›Full record

ArticleWellcome open research2018

Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse.

Chiara Beilin, Kaushik Choudhuri, Gerben Bouma, Dessislava Malinova, Jaime Llodra, David L Stokes, Motumu Shimaoka, Timothy A Springer, Michael L Dustin, Adrian J Thrasher and 1 more

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Chiara Beilin *Molecular Immunology Unit, Institute of Child Health, University College London, London, WC1N 1EH, UK.ORCID https://orcid.org/0000-0003-1574-3256
Kaushik Choudhuri *Program in Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, New York University, New York, NY, 10016, USA.ORCID https://orcid.org/0000-0002-3911-027X
Gerben BoumaMolecular Immunology Unit, Institute of Child Health, University College London, London, WC1N 1EH, UK.ORCID https://orcid.org/0000-0002-1465-9178
Dessislava MalinovaMolecular Immunology Unit, Institute of Child Health, University College London, London, WC1N 1EH, UK.ORCID https://orcid.org/0000-0003-0784-5703
Jaime LlodraProgram in Structural Biology, Skirball Institute of Biomolecular Medicine, New York University, New York, NY, 10016, USA.
David L StokesProgram in Structural Biology, Skirball Institute of Biomolecular Medicine, New York University, New York, NY, 10016, USA.
Motumu ShimaokaImmune Disease Institute, Children's Hospital Boston, Boston, MA, 02115, USA.
Timothy A SpringerProgram in Structural Biology, Skirball Institute of Biomolecular Medicine, New York University, New York, NY, 10016, USA.ORCID https://orcid.org/0000-0001-6627-2904
Michael L DustinProgram in Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, New York University, New York, NY, 10016, USA.ORCID https://orcid.org/0000-0003-4983-6389
Adrian J ThrasherMolecular Immunology Unit, Institute of Child Health, University College London, London, WC1N 1EH, UK.
Siobhan O BurnsGreat Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, UK.ORCID https://orcid.org/0000-0002-3356-9506
New York University · USUniversity College London · GBBoston Children's Hospital · USGreat Ormond Street Hospital for Children NHS Foundation Trust · GBRoyal Free London NHS Foundation Trust · GBUniversity of Oxford · GB

Funding

LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGENSR01CA031798 · NCI · IMMUNE DISEASE INSTITUTE, INC. · PI SPRINGER, TIMOTHY A · 1985 to 2018
$5.1M
Requirement for Sensitive T Cell Response to AntigenR37AI043542 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DUSTIN, MICHAEL LORAN · 2007 to 2016
$3.6M
NCI NIH HHS R01 CA031798NIAID NIH HHS R37 AI043542Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

dendritic cellsimmunodeficiencyimmunological synapseinterleukinslymphocytestrans-presentation

Identifiers

PMID30483599
PMCPMC6234741
OpenAlexW2884409529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.