Evidence map›Paper›PMID 30483515›Full record

ArticleFrontiers in molecular biosciences2018

The Hypervariable Loops of Free TCRs Sample Multiple Distinct Metastable Conformations in Solution.

James E Crooks, Christopher T Boughter, L Ridgway Scott, Erin J Adams

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

James E CrooksGraduate Program in Biophysical Sciences, University of Chicago, Chicago, IL, United States.
Christopher T BoughterGraduate Program in Biophysical Sciences, University of Chicago, Chicago, IL, United States.
L Ridgway ScottDepartment of Computer Science, University of Chicago, Chicago, IL, United States.
Erin J AdamsCommittee on Immunology University of Chicago, Chicago, IL, United States.
University of Chicago · US

Funding

Graduate Program in Biophysical Sciences at the University of Chicago - Renewal 0T32EB009412 · NIBIB · UNIVERSITY OF CHICAGO · PI ENGEL, GREGORY S, SOSNICK, TOBIN R · 2009 to 2023
$4.9M
Molecular Recognition of Ligand by the Gamma Delta T Cell ReceptorR01AI073922 · NIAID · UNIVERSITY OF CHICAGO · PI ADAMS, ERIN JUNE · 2007 to 2016
$3.8M
NIAID NIH HHS R01 AI073922NIBIB NIH HHS T32 EB009412
6 · The paper itself

Abstract

CD4

Indexed as

adaptive immunityindependent component (IC) analysisinnate immunitymarkov state modelsmolecular dynamics (MD)T cell receptor dynamics

Identifiers

PMID30483515
PMCPMC6243104
OpenAlexW2901500430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.