Evidence map›Paper›PMID 30483514›Full record

ArticleFrontiers in molecular biosciences2018

Conformational Change Induced by Putidaredoxin Binding to Ferrous CO-ligated Cytochrome P450cam Characterized by 2D IR Spectroscopy.

Sashary Ramos, Edward J Basom, Megan C Thielges

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Transparent window 2D IR spectroscopy of proteins.The Journal of chemical physics · 2021
    Review
  2. Protein Dynamics by Two-Dimensional Infrared Spectroscopy.Annual review of analytical chemistry (Palo Alto, Calif.) · 2021
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sashary RamosDepartment of Chemistry, Indiana University, Bloomington, IN, United States.
Edward J BasomDepartment of Chemistry, Indiana University, Bloomington, IN, United States.
Megan C ThielgesDepartment of Chemistry, Indiana University, Bloomington, IN, United States.
Indiana University Bloomington · US

Funding

Conformations and Dynamics of Cytochrome P450s via 2D Infrared SpectroscopyR01GM114500 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI THIELGES, MEGAN CORRINE · 2017 to 2022
$1.1M
Graduate Program in Quantitative and Chemical Biology at Indiana University BloomT32GM109825 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI GIEDROC, DAVID P. · 2014 to 2018
$926k
Protein Dynamics and Substrate Specificity in Cytochrome P450sF32GM090549 · NIGMS · STANFORD UNIVERSITY · PI THIELGES, MEGAN CORRINE · 2010 to 2012
$120k
NIGMS NIH HHS F32 GM090549NIGMS NIH HHS R01 GM114500NIGMS NIH HHS T32 GM109825
6 · The paper itself

Abstract

The importance of conformational dynamics to protein function is now well-appreciated. An outstanding question is whether they are involved in the effector role played by putidaredoxin (Pdx) in its reduction of the O

Indexed as

2D IR spectroscopycytochrome P450energy landscapeinfrared spectroscopyprotein dynamicsputidaredoxin

Identifiers

PMID30483514
PMCPMC6243089
OpenAlexW2901050072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.