Evidence map›Paper›PMID 30483479›Full record

ArticleFrontiers in cellular and infection microbiology2018

A Wor1-Like Transcription Factor Is Essential for Virulence of

Hugo Costa Paes, Lorena da Silveira Derengowski, Luisa Defranco Ferreira Peconick, Patrícia Albuquerque, Georgios Joannis Pappas, André Moraes Nicola, Fabiana Brandão Alves Silva, Marcelo Afonso Vallim, J Andrew Alspaugh, Maria Sueli Soares Felipe and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Hugo Costa PaesClinical Medicine Division, University of Brasília Medical School, Brasília, Brazil.
Lorena da Silveira DerengowskiMilitary College, Brasília, Brazil.
Luisa Defranco Ferreira PeconickCeilândia College, University of Brasília, Brasília, Brazil.
Patrícia AlbuquerqueCeilândia College, University of Brasília, Brasília, Brazil.
Georgios Joannis PappasDepartment of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília, Brazil.
André Moraes NicolaPathology Division, University of Brasília Medical School, Brasília, Brazil.
Fabiana Brandão Alves SilvaDepartment of Biomedicine, Paulista University, Brasília, Brazil.
Marcelo Afonso VallimCellular and Molecular Biology Division, Biological Sciences Department, São Paulo Federal University, São Paulo, Brazil.
J Andrew AlspaughDepartment of Medicine, School of Medicine, Duke University, Durham, NC, United States.
Maria Sueli Soares FelipeGraduate School in Genomic Sciences, Catholic University of Brasília, Brasília, Brazil.
Larissa FernandesCeilândia College, University of Brasília, Brasília, Brazil.
Universidade de Brasília · BRDuke University · USUniversidade Católica de Brasília · BRUniversidade Federal de São Paulo · BRUniversidade Paulista · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gti1/Pac2 transcription factors occur exclusively in fungi and their roles vary according to species, including regulating morphological transition and virulence, mating and secondary metabolism. Many of these functions are important for fungal pathogenesis. We therefore hypothesized that one of the two proteins of this family in

Indexed as

AnimalsCryptococcosisCryptococcus neoformansCytokinesisDisease Models, AnimalGene DeletionGene Expression ProfilingLepidopteraMicePolysaccharidesSequence Analysis, RNATemperatureTranscription FactorsVirulencePolysaccharidesTranscription FactorscapsuleCryptococcus neoformanscytokinesistranscription factorvirulence

Identifiers

PMID30483479
PMCPMC6243373
OpenAlexW2900476085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.