Evidence map›Paper›PMID 30483384›Full record

ArticleIranian journal of basic medical sciences2018

The effects of bortezomib on the ovariectomy applied rat uterus: A histopathological, stereological, and immunohistochemical study.

Habib Khoshvaghti, Berrin Zuhal Altunkaynak

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of basic medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Habib KhoshvaghtiDepartment of Histology and Embryology, Medical Faculty, Bülent Ecevit University, Zonguldak, Turkey.
Berrin Zuhal AltunkaynakDepartment of Histology and Embryology, Medical Faculty, İstanbul Okan University, İstanbul, Turkey.
Bülent Ecevit University · TROkan University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn this study, potential protective effects of Bortezomib (Bort), as a proteasome inhibitor, were investigated on the uterus of ovariectomized rats by histological, morphometric and immunohistochemical methods. MATERIALS AND

methodsIn this study, 18

resultsMorphometric and histopathological evaluations showed that Bort was effective in the uterus and protects the layer structures and the cells.

conclusionIn the light of these findings, we suggest that for proteasome inhibitor particularly Bort is thought to be useful through proteasome inhibition and NF-κB pathway.

Indexed as

BortezomibMicroscopyOvariectomyRatStereologyUterus

Identifiers

PMID30483384
PMCPMC6251398
OpenAlexW2898429306

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.