ArticleIranian journal of microbiology2018
Prevalence of dengue and leptospirosis co-infection in a tertiary care hospital in south India.
Article in Iranian journal of microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Leptospirosis and its co-infections in India: prevalence, geographic distribution, and clinical implications.BMC infectious diseases · 2026Pooled it
- Prevalence of dengue and leptospirosis coinfection and associated mortality rates: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Clinical and epidemiological profile of hospitalized patients with leptospirosis: a cross-sectional study in Durán, Ecuador, 2023.Frontiers in cellular and infection microbiology · 2026Article
- Flood-associated disease outbreaks and transmission in Southeast Asia.Frontiers in microbiology · 2025Review
- Dengue and leptospirosis coinfection: a case series.Journal of medical case reports · 2024Article
- Distribution, frequency and clinical presentation of leptospirosis and coinfections: a systematic review protocol.BMJ open · 2022Article
- Putative Pathogenic Genes ofTropical medicine and infectious disease · 2022Article
- Leptospirosis and Coinfection: Should We Be Concerned?International journal of environmental research and public health · 2021Review
- Leptospirosis in febrile patients with suspected diagnosis of dengue fever.BMC research notes · 2021Article
- Leptospiral Infection, Pathogenesis and Its Diagnosis-A Review.Pathogens (Basel, Switzerland) · 2021Review
- Leptospira interrogans and Leptospira kirschneri are the dominant Leptospira species causing human leptospirosis in Central Malaysia.PLoS neglected tropical diseases · 2020Article
- Usefulness of C-Reactive Protein in Differentiating Acute Leptospirosis and Dengue Fever in French Guiana.Open forum infectious diseases · 2019Article
- Acute Kidney Injury and Jaundice in a Patient With Concurrent Severe Malaria and Acute Exacerbation of Hepatitis B.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesDengue and Leptospirosis were often discussed separately with rash being more common in dengue and jaundice in leptospirosis. But with increasing reports of co-infection, the situation has become worse. The main objective of this study was to look for the presence of both Dengue and Leptospira IgM antibodies in serum samples of patients, presenting with acute febrile illness. Medical records of the co-infected patients were examined to analyse the clinical features and laboratory findings. MATERIALS AND
methodsSerum samples of patients presenting with acute febrile illness were screened for the presence of Dengue IgM antibodies and Leptospira antibodies. Clinical features and laboratory parameters of patients with co-infection were compared with patients having dengue alone. Rainfall data was obtained to look for an association between rainfall and Dengue, leptospirosis and co-infected cases.
resultsCo-infection was seen in 33 (3.4%) samples. There was a statistically significant association between clinical features like rashes, bleeding gums and co-infection. There was a statistically significant association between various laboratory parameters like thrombocytopenia and co-infection. There was positive correlation between rainfall and development of dengue, leptospirosis, and co-infection but it was not statistically significant.
conclusionThe overall prevalence of co-infection was 3.4%. This study re-emphasizes the fact that dengue and leptospirosis are widely prevalent in south India and clinicians should be aware that co-infection with dengue and leptospirosis is not uncommon.
Indexed as
Identifiers
30483374PMC6243148W2895360593What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.