Evidence map›Paper›PMID 30483264›Full record

ArticleFrontiers in immunology2018

Importance of EMT Factor ZEB1 in cDC1 "MutuDC Line" Mediated Induction of Th1 Immune Response.

Shuchi Smita, Abdul Ahad, Arup Ghosh, Viplov K Biswas, Marianna M Koga, Bhawna Gupta, Hans Acha-Orbea, Sunil K Raghav

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Cellular Assays to Monitor Antigen Cross-presentation In Vitro.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Corneal injury repair and the potential involvement of ZEB1.Eye and vision (London, England) · 2024
    Review
  8. Article
  9. Article
  10. ZEB1-activated Notch1 promotes circulating tumor cell migration and invasion in lung squamous cell carcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Article
  11. Article
  12. Review
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Shuchi SmitaImmuno-genomics and Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, India.
Abdul AhadImmuno-genomics and Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, India.
Arup GhoshImmuno-genomics and Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, India.
Viplov K BiswasImmuno-genomics and Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, India.
Marianna M KogaDepartment of Biochemistry CIIL, University of Lausanne (UNIL), Epalinges, Switzerland.
Bhawna GuptaDepartment of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Bhubaneswar, India.
Hans Acha-OrbeaDepartment of Biochemistry CIIL, University of Lausanne (UNIL), Epalinges, Switzerland.
Sunil K RaghavImmuno-genomics and Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, India.
Indian Institute of Technology Bhubaneswar · INManipal Academy of Higher Education · INUniversity of Lausanne · CHInstitute of Life Sciences · INKIIT University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of Epithelial to Mesenchymal Transition (EMT) factor Zeb1 is well defined in metastasis and cancer progression but it's importance in dendritic cells (DCs) is unexplored until now. For the first time we report here that Zeb1 controls immunogenic responses of CD8α

Indexed as

Adaptive ImmunityAdoptive TransferAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell DifferentiationCells, CulturedCoculture TechniquesDendritic CellsEpithelial-Mesenchymal TransitionFemaleHEK293 CellsHumansInterleukin-10Interleukin-12Interleukin-6Interleukin-10Interleukin-12Interleukin-6Toll-Like Receptor 9ZEB1 protein, mouseZinc Finger E-box-Binding Homeobox 1cDC1 dendritic cellsChIP-seqhelminth infectionimmune modulationintegrative genomicsRNA-seqTh2 responseZEB1

Identifiers

PMID30483264
PMCPMC6243008
OpenAlexW2900865908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.