Evidence map›Paper›PMID 30483247›Full record

ReviewFrontiers in immunology2018

Advances in Designing and Developing Vaccines, Drugs and Therapeutic Approaches to Counter Human Papilloma Virus.

Maryam Dadar, Sandip Chakraborty, Kuldeep Dhama, Minakshi Prasad, Rekha Khandia, Sameer Hassan, Ashok Munjal, Ruchi Tiwari, Kumaragurubaran Karthik, Deepak Kumar and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 4 countries.

Maryam DadarRazi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization, Karaj, Iran.
Sandip ChakrabortyDepartment of Veterinary Microbiology, College of Veterinary Sciences and Animal Husbandry, West Tripura, India.
Kuldeep DhamaDivision of Pathology, ICAR-Indian Veterinary Research Institute, Bareilly, India.
Minakshi PrasadDepartment of Animal Biotechnology, LLR University of Veterinary and Animal Sciences, Hisar, India.
Rekha KhandiaDepartment of Genetics, Barkatullah University, Bhopal, India.
Sameer HassanDepartment of Biomedical Informatics, National Institute for Research in Tuberculosis, Indian Council of Medical Research, Chennai, India.
Ashok MunjalDepartment of Genetics, Barkatullah University, Bhopal, India.
Ruchi TiwariDepartment of Veterinary Microbiology and Immunology, College of Veterinary Sciences, U P Pt. Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go-Anusandhan Sansthan, Mathura, India.
Kumaragurubaran KarthikCentral University Laboratory, Tamil Nadu Veterinary and Animal Sciences University, Chennai, India.
Deepak KumarDivision of Veterinary Biotechnology, ICAR-Indian Veterinary Research Institute, Bareilly, India.
Hafiz M N IqbalTecnologico de Monterrey, School of Engineering and Sciences, Monterrey, Mexico.
Wanpen ChaicumpaDepartment of Parasitology, Center of Research Excellence on Therapeutic Proteins and Antibody Engineering, Faculty of Medicine SIriraj Hospital, Mahidol University, Bangkok, Thailand.
Barkatullah University · INIndian Veterinary Research Institute · INAgricultural Research & Education Organization · IRIndian Council of Medical Research · INLala Lajpat Rai University of Veterinary and Animal Sciences · INMahidol University · THTamil Nadu Veterinary and Animal Sciences University · INTecnológico de Monterrey · MXUttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human papillomavirus (HPV) is a viral infection with skin-to-skin based transmission mode. HPV annually caused over 500,000 cancer cases including cervical, anogenital and oropharyngeal cancer among others. HPV vaccination has become a public-health concern, worldwide, to prevent the cases of HPV infections including precancerous lesions, cervical cancers, and genital warts especially in adolescent female and male population by launching national programs with international alliances. Currently, available prophylactic and therapeutic vaccines are expensive to be used in developing countries for vaccination programs. The recent progress in immunotherapy, biotechnology, recombinant DNA technology and molecular biology along with alternative and complementary medicinal systems have paved novel ways and valuable opportunities to design and develop effective prophylactic and therapeutic vaccines, drugs and treatment approach to counter HPV effectively. Exploration and more researches on such advances could result in the gradual reduction in the incidences of HPV cases across the world. The present review presents a current global scenario and futuristic prospects of the advanced prophylactic and therapeutic approaches against HPV along with recent patents coverage of the progress and advances in drugs, vaccines and therapeutic regimens to effectively combat HPV infections and its cancerous conditions.

Indexed as

AdolescentAntiviral AgentsCondylomata AcuminataDrug DesignDrug DevelopmentFemaleHumansImmunization ProgramsMaleOropharyngeal NeoplasmsPapillomaviridaePapillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsVaccinationAntiviral AgentsPapillomavirus Vaccinesdrugshuman papilloma virus (HPV)prophylaxistherapyvaccines

Identifiers

PMID30483247
PMCPMC6240620
OpenAlexW2896239333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.