Evidence map›Paper›PMID 30483134›Full record

ArticleFrontiers in pharmacology2018

Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of

Santosh Kumar Adla, Barbora Slavikova, Hana Chodounska, Vojtech Vyklicky, Marek Ladislav, Pavla Hubalkova, Barbora Krausova, Tereza Smejkalova, Michaela Nekardova, Marketa Smidkova and 4 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Positive modulators ofRSC advances · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Santosh Kumar AdlaInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czechia.
Barbora SlavikovaInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czechia.
Hana ChodounskaInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czechia.
Vojtech VyklickyInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Marek LadislavInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Pavla HubalkovaInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Barbora KrausovaInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Tereza SmejkalovaInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Michaela NekardovaInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czechia.
Marketa SmidkovaInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czechia.
Lenka MonincovaInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czechia.
Radko SoucekInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czechia.
Ladislav VyklickyInstitute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Eva KudovaInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czechia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report the synthesis, structure-activity relationship study, and biological evaluation of neurosteroid inhibitors of

Indexed as

amideneurosteroidNMDA receptorplasma stabilitystructure-activity relationship

Identifiers

PMID30483134
PMCPMC6240685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.