ArticleFrontiers in human neuroscience2018
Functional Connectivity During Handgrip Motor Fatigue in Older Adults Is Obesity and Sex-Specific.
Article in Frontiers in human neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- A Systematic Review of the Application of Functional Near-Infrared Spectroscopy to the Study of Cerebral Hemodynamics in Healthy Aging.Neuropsychology review · 2021Pooled it
- Learning selection-based augmented reality interactions across different training modalities: uncovering sex-specific neural strategies.Frontiers in neuroergonomics · 2025Article
- A single 1,500 m freestyle at maximal speed decreases cognitive function in athletes.Frontiers in psychology · 2023Article
- Obesity and Poststroke Fatigue: A 2-Year Longitudinal Study.Neurology and therapy · 2021Article
- The Exercising Brain: An Overlooked Factor Limiting the Tolerance to Physical Exertion in Major Cardiorespiratory Diseases?Frontiers in human neuroscience · 2021Review
- Evaluation and Test Methods of Industrial Exoskeletons In Vitro, In Vivo, and In Silico: A Critical Review.Critical reviews in biomedical engineering · 2021Review
- A Methodological Framework to Capture Neuromuscular Fatigue Mechanisms Under Stress.Frontiers in neuroergonomics · 2021Review
- Transcranial photobiomodulation-induced changes in human brain functional connectivity and network metrics mapped by whole-head functional near-infrared spectroscopyBiomedical optics express · 2020Article
- Differences in Net Information Flow and Dynamic Connectivity Metrics Between Physically Active and Inactive Subjects Measured by Functional Near-Infrared Spectroscopy (fNIRS) During a Fatiguing Handgrip Task.Frontiers in neuroscience · 2020Article
- Neural Signatures of Handgrip Fatigue in Type 1 Diabetic Men and Women.Frontiers in human neuroscience · 2020Article
- Mapping cortical network effects of fatigue during a handgrip task by functional near-infrared spectroscopy in physically active and inactive subjects.Neurophotonics · 2019Article
- Neural Efficiency of Human-Robotic Feedback Modalities Under Stress Differs With Gender.Frontiers in human neuroscience · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The prevalence of obesity in older adults, particularly in females, is increasing rapidly and is associated with declines in both the brain and physical health. Both the obese and the female populations have shown greater motor fatigue than their counterparts, however, the central neural mechanisms for fatigue are unclear. The present study measured fatigue-related functional connectivity across frontal and sensorimotor areas using functional near-infrared spectroscopy (fNIRS). Fifty-nine older adults (30 non-obese and 29 obese) performed submaximal handgrip motor fatigue until voluntary exhaustion. Functional connectivity and cerebral hemodynamics were compared across eight cortical areas during motor fatigue and across obesity and sex groups along with neuromuscular fatigue outcomes (i.e., endurance time, strength loss, and force steadiness). Both obesity- and sex-specific functional architecture and mean activation differences during motor fatigue in older adults were observed, which were accompanied by fatigue-related changes in variability of force steadiness that differed between groups. While primary indicators of fatigue, i.e., endurance and strength loss, did not differ between groups, the motor steadiness changes indicated different neural adaptation strategies between the groups. These findings indicate that obesity and sex differences exist in brain function in older adults, which may affect performance during motor fatigue.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.