Evidence map›Paper›PMID 30483057›Full record

ReviewFrontiers in cellular neuroscience2018

Cell-Biological Requirements for the Generation of Dentate Gyrus Granule Neurons.

Maryam Hatami, Sabine Conrad, Pooyan Naghsh, Gonzalo Alvarez-Bolado, Thomas Skutella

Abstract readReview
In one paragraph

Review in Frontiers in cellular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Single-cell map of the female brain across reproductive transitions.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Partial Deletion ofeNeuro · 2026
    Article
  4. Article
  5. Article
  6. Article
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  9. Review
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  12. Neurogenesis From Embryo to Adult - Lessons From Flies and Mice.Frontiers in cell and developmental biology · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maryam HatamiInstitute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany.
Sabine ConradIndependent Researcher, Tübingen, Germany.
Pooyan NaghshDepartment of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada.
Gonzalo Alvarez-BoladoInstitute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany.
Thomas SkutellaInstitute for Anatomy and Cell Biology, Heidelberg University, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dentate gyrus (DG) receives highly processed information from the associative cortices functionally integrated in the trisynaptic hippocampal circuit, which contributes to the formation of new episodic memories and the spontaneous exploration of novel environments. Remarkably, the DG is the only brain region currently known to have high rates of neurogenesis in adults (Andersen et al., 1966, 1971). The DG is involved in several neurodegenerative disorders, including clinical dementia, schizophrenia, depression, bipolar disorder and temporal lobe epilepsy. The principal neurons of the DG are the granule cells. DG granule cells generated in culture would be an ideal model to investigate their normal development and the causes of the pathologies in which they are involved and as well as possible therapies. Essential to establish such

Indexed as

dentate gyrusgranule cellsinduced pluripotent stem cells (iPSC)in vitrorequirements

Identifiers

PMID30483057
PMCPMC6240695

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.