Evidence map›Paper›PMID 30482851›Full record

ArticleScience signaling2018

Hippocampal mGluR1-dependent long-term potentiation requires NAADP-mediated acidic store Ca

William J Foster, Henry B C Taylor, Zahid Padamsey, Alexander F Jeans, Antony Galione, Nigel J Emptage

Abstract read
In one paragraph

Article in Science signaling, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. The how and why for multiple forms of hippocampal LTP.Frontiers in synaptic neuroscience · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Endolysosomal TPCs regulate social behavior by controlling oxytocin secretion.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Article
  14. Intracellular CaFrontiers in physiology · 2023
    Review
  15. Article
  16. GABACells · 2022
    Article
  17. Article
  18. Two-pore channels: going with the flows.Biochemical Society transactions · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

William J FosterDepartment of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK. william.foster@pharm.ox.ac.uk nigel.emptage@pharm.ox.ac.uk antony.galione@pharm.ox.ac.uk.ORCID 0000-0002-4322-9521
Henry B C TaylorDepartment of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK.ORCID 0000-0003-3669-3593
Zahid PadamseyDepartment of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK.
Alexander F JeansDepartment of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK.ORCID 0000-0002-4004-3676
Antony GalioneDepartment of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK. william.foster@pharm.ox.ac.uk nigel.emptage@pharm.ox.ac.uk antony.galione@pharm.ox.ac.uk.ORCID 0000-0002-4132-7646
Nigel J EmptageDepartment of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK. william.foster@pharm.ox.ac.uk nigel.emptage@pharm.ox.ac.uk antony.galione@pharm.ox.ac.uk.ORCID 0000-0002-7348-497X
University of Oxford · GB

Funding

Biotechnology and Biological Sciences Research CouncilWellcome Trust 102828
6 · The paper itself

Abstract

Acidic organelles, such as endosomes and lysosomes, store Ca

Indexed as

Calcium SignalingLong-Term PotentiationAnimalsCalciumCalcium ChannelsCells, CulturedHippocampusMaleMiceMice, KnockoutNADPPyramidal CellsRatsRats, WistarReceptors, Metabotropic GlutamateTwo-Pore ChannelsCalciumCalcium Channelsmetabotropic glutamate receptor type 1NAADPNADPReceptors, Metabotropic GlutamateTPCN1 protein, mouseTPCN2 protein, mouseTwo-Pore Channels

Identifiers

PMID30482851
PMCPMC6679716
OpenAlexW2902806650

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.