Evidence map›Paper›PMID 30482834›Full record

ArticlemBio2018

Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like

Corinne E Rouquette-Loughlin, Jennifer L Reimche, Jacqueline T Balthazar, Vijaya Dhulipala, Kim M Gernert, Ellen N Kersh, Cau D Pham, Kevin Pettus, A Jeanine Abrams, David L Trees and 2 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 95 citations in OpenAlex.

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  17. Structural analysis of resistance-nodulation cell division transporters.Microbiology and molecular biology reviews : MMBR · 2024
    Review
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  19. Rolling the evolutionary dice:Microbiology spectrum · 2024
    Article
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Corinne E Rouquette-LoughlinDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.
Jennifer L ReimcheDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.
Jacqueline T BalthazarDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.
Vijaya DhulipalaDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.
Kim M GernertDivision of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA.
Ellen N KershDivision of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA.
Cau D PhamDivision of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA.
Kevin PettusDivision of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA.
A Jeanine AbramsDivision of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA.
David L TreesDivision of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA.
Sancta St CyrDivision of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, Georgia, USA.
William M ShaferDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA wshafer@emory.edu.
Emory University · USNational Center for HIV/AIDS Viral Hepatitis STD and TB Prevention · USCenters for Disease Control and Prevention · USUnited States Department of Health and Human Services · US

Funding

Gonococci: Genetics of Resistance to PMN ProteinsR37AI021150 · NIAID · EMORY UNIVERSITY · PI SHAFER, WILLIAM MAURICE · 2010 to 2019
$3.9M
NIAID NIH HHS R37 AI021150
6 · The paper itself

Abstract

Recent reports suggest that mosaic-like sequences within the

Indexed as

Drug Resistance, BacterialAnti-Infective AgentsAzithromycinBiological Transport, ActiveGene Expression Regulation, BacterialMembrane Transport ProteinsMutationNeisseria gonorrhoeaeOperonPromoter Regions, GeneticRepressor ProteinsTranscription, GeneticAnti-Infective AgentsAzithromycinMembrane Transport ProteinsRepressor Proteinsantibiotic resistanceeffluxgonorrheamolecular geneticstransformation

Identifiers

PMID30482834
PMCPMC6282211
OpenAlexW2952412926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.