Evidence map›Paper›PMID 30482764›Full record

GuidelineBlood advances2018

American Society of Hematology 2018 guidelines for management of venous thromboembolism: diagnosis of venous thromboembolism.

Wendy Lim, Grégoire Le Gal, Shannon M Bates, Marc Righini, Linda B Haramati, Eddy Lang, Jeffrey A Kline, Sonja Chasteen, Marcia Snyder, Payal Patel and 7 more

Registry-linked trialAbstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05413317 (Contribution of Lower Limb Venous Colour Doppler Ultrasound in the Diagnosis of Pulmonary Embolism Recurrence), which is not on this map. Cited by 180 papers, 22 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
180citing papers in PubMed, 22 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05413317 completednot on this mapstarted 2022, after this paper: background citation

Contribution of Lower Limb Venous Colour Doppler Ultrasound in the Diagnosis of Pulmonary Embolism Recurrence

TypeobservationalSponsorCentre Hospitalier Intercommunal de Toulon La Seyne sur MerRan2022 to 2023Enrolled115ConditionsPulmonary EmbolismArmsColor Doppler Ultrasound
3 · Its place in the literature

Who cites it

180 citing papers in PubMed, 22 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Antithrombotic prophylaxis following total knee arthroplasty: a level I Bayesian network meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
    Pooled it
  4. Antithrombotic prophylaxis following total hip arthroplasty: a level I Bayesian network meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2024
    Pooled it
  5. Guideline
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  9. Guideline
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  13. Predictive roles of D-dimer for mortality of patients with community-acquired pneumonia: a systematic review and meta-analysis.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2021
    Pooled it
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  15. Guideline
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120 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Wendy LimDepartment of Medicine and.ORCID 0000-0003-2508-1786
Grégoire Le GalDepartment of Medicine, University of Ottawa/Ottawa Hospital Research Institute, Ottawa, ON, Canada.ORCID 0000-0002-9253-248X
Shannon M BatesDepartment of Medicine and.
Marc RighiniDivision of Angiology and Hemostasis, Department of Medical Specialties, Geneva University Hospitals, Geneva, Switzerland.
Linda B HaramatiDepartment of Radiology and.
Eddy LangDepartment of Emergency Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Jeffrey A KlineDepartment of Emergency Medicine, School of Medicine, Indiana University, Indianapolis, IN.
Sonja ChasteenFort Myers, FL.
Marcia SnyderWheaton, IL.
Payal PatelDepartment of Emergency Medicine, University of Illinois at Chicago, Chicago, IL.
Meha BhattDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Parth PatelDepartment of Internal Medicine, School of Medicine, University of Missouri-Kansas City, Kansas City, MO.ORCID 0000-0002-4864-4927
Cody BraunDepartment of Medicine, Loyola University Medical Center, Maywood, IL; and.
Housne BegumDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Wojtek WierciochDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.ORCID 0000-0001-6576-1650
Holger J SchünemannDepartment of Medicine and.
Reem A MustafaDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.ORCID 0000-0002-2091-0875

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundModern diagnostic strategies for venous thromboembolism (VTE) incorporate pretest probability (PTP; prevalence) assessment. The ability of diagnostic tests to correctly identify or exclude VTE is influenced by VTE prevalence and test accuracy characteristics.

objectiveThese evidence-based guidelines are intended to support patients, clinicians, and health care professionals in VTE diagnosis. Diagnostic strategies were evaluated for pulmonary embolism (PE), deep vein thrombosis (DVT) of the lower and upper extremity, and recurrent VTE.

methodsThe American Society of Hematology (ASH) formed a multidisciplinary panel including patient representatives. The McMaster University GRADE Centre completed systematic reviews up to 1 October 2017. The panel prioritized questions and outcomes and used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to assess evidence and make recommendations. Test accuracy estimates and VTE population prevalence were used to model expected outcomes in diagnostic pathways. Where modeling was not feasible, management and accuracy studies were used to formulate recommendations.

resultsTen recommendations are presented, by PTP for patients with suspected PE and lower extremity DVT, and for recurrent VTE and upper extremity DVT.

conclusionsFor patients at low (unlikely) VTE risk, using D-dimer as the initial test reduces the need for diagnostic imaging. For patients at high (likely) VTE risk, imaging is warranted. For PE diagnosis, ventilation-perfusion scanning and computed tomography pulmonary angiography are the most validated tests, whereas lower or upper extremity DVT diagnosis uses ultrasonography. Research is needed on new diagnostic modalities and to validate clinical decision rules for patients with suspected recurrent VTE.

Indexed as

Computed Tomography AngiographyFibrin Fibrinogen Degradation ProductsHumansPulmonary EmbolismUltrasonographyUpper Extremity Deep Vein ThrombosisVenous ThromboembolismVenous ThrombosisVentilation-Perfusion ScanFibrin Fibrinogen Degradation Productsfibrin fragment D

Identifiers

PMID30482764
PMCPMC6258916

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.