Evidence map›Paper›PMID 30482763›Full record

GuidelineBlood advances2018

American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients.

Holger J Schünemann, Mary Cushman, Allison E Burnett, Susan R Kahn, Jan Beyer-Westendorf, Frederick A Spencer, Suely M Rezende, Neil A Zakai, Kenneth A Bauer, Francesco Dentali and 9 more

Erratum issued 2 registry-linked trialsOpen access · goldAbstract readPractice Guideline
In one paragraph

Guideline in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 388 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
388citing papers in PubMed, 17 pooled it
68.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05498142 unknown statusnot on this map

Predicting the Risk of Venous Thromboembolism in Critically Ill Patients: Validation of Pre-existing Risk Prediction Models and Development of a Prediction Model

Typeobservational_patient_registrySponsorUniversity Medical Center GroningenRan2015 to 2023Enrolled7,600ConditionsVenous Thromboembolism, Critical Illness
NCT06958588 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Pulsed Electromagnetic Field Therapy (PEMF) Compared to Conventional Mechanical Prophylaxis for Venous Thromboembolism Prophylaxis in Patients in the Intensive Care Unit (ICU)

TypeinterventionalSponsorScience Valley Research InstituteRan2025 to 2026Enrolled50ConditionsVenous Thromboembolism (VTE), Intensive Care Medicine, Venous ThromboembolismArmsExperimental: Hyperslim, Active Comparator #1
3 · Its place in the literature

Who cites it

388 citing papers in PubMed, 17 syntheses or guidelines pooled it, 782 citations in OpenAlex.

  1. Guideline
  2. Guideline
  3. Pooled it
  4. Guideline
  5. Pooled it
  6. Guideline
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Guideline
  14. Pooled it
  15. Travel-Associated Venous Thromboembolism.Wilderness & environmental medicine · 2022
    Pooled it
  16. Pooled it
  17. Guideline
  18. Trial
  19. Trial
  20. Sex differences in thromboprophylaxis of the critically ill: a secondary analysis of a randomized trial.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Trial

328 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 13 institutions in 7 countries.

Holger J SchünemannDepartment of Medicine and.
Mary CushmanDepartment of Medicine and.
Allison E BurnettInpatient Antithrombosis Service, University of New Mexico Health Sciences Center, Albuquerque, NM.
Susan R KahnDepartment of Medicine, McGill University and Lady Davis Institute, Montreal, QC, Canada.
Jan Beyer-WestendorfThrombosis Research Unit, Division of Hematology, Department of Medicine I, University Hospital "Carl Gustav Carus," Dresden, Germany.
Frederick A SpencerDepartment of Medicine and.
Suely M RezendeDepartment of Internal Medicine, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Neil A ZakaiDepartment of Medicine and.
Kenneth A BauerDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Francesco DentaliDepartment of Medicine and Surgery, Insubria University, Varese, Italy.
Jill LansingState University of New York, Albany, NY.
Sara BalduzziCochrane Italy, Department of Diagnostic, Clinical and Public Health Medicine, University of Modena and Reggio Emilia, Modena, Italy; and.
Andrea DarziDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Gian Paolo MorganoDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Ignacio NeumannDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Robby NieuwlaatDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Juan J Yepes-NuñezDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Yuan ZhangDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Wojtek WierciochDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Impact · CAMcMaster University · CAHarvard University · USKing's College London · GBMcGill University · CAPontificia Universidad Católica de Chile · CLUniversidade Federal de Minas Gerais · BRUniversity at Albany, State University of New York · USUniversity of Insubria · ITUniversity of Modena and Reggio Emilia · ITUniversity of New Mexico · USUniversity of Vermont · USUniversity of Vermont Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVenous thromboembolism (VTE) is the third most common vascular disease. Medical inpatients, long-term care residents, persons with minor injuries, and long-distance travelers are at increased risk.

objectiveThese evidence-based guidelines from the American Society of Hematology (ASH) intend to support patients, clinicians, and others in decisions about preventing VTE in these groups.

methodsASH formed a multidisciplinary guideline panel balanced to minimize potential bias from conflicts of interest. The McMaster University GRADE Centre supported the guideline-development process, including updating or performing systematic evidence reviews. The panel prioritized clinical questions and outcomes according to their importance for clinicians and adult patients. The Grading of Recommendations Assessment, Development and Evaluation approach was used to assess evidence and make recommendations, which were subject to public comment.

resultsThe panel agreed on 19 recommendations for acutely ill and critically ill medical inpatients, people in long-term care facilities, outpatients with minor injuries, and long-distance travelers.

conclusionsStrong recommendations included provision of pharmacological VTE prophylaxis in acutely or critically ill inpatients at acceptable bleeding risk, use of mechanical prophylaxis when bleeding risk is unacceptable, against the use of direct oral anticoagulants during hospitalization, and against extending pharmacological prophylaxis after hospital discharge. Conditional recommendations included not to use VTE prophylaxis routinely in long-term care patients or outpatients with minor VTE risk factors. The panel conditionally recommended use of graduated compression stockings or low-molecular-weight heparin in long-distance travelers only if they are at high risk for VTE.

Indexed as

AnticoagulantsDrug Administration ScheduleEvidence-Based MedicineHeparinHeparin, Low-Molecular-WeightHospitalizationHumansPost-Exposure ProphylaxisSocieties, MedicalVenous ThromboembolismAnticoagulantsHeparinHeparin, Low-Molecular-Weight

Identifiers

PMID30482763
PMCPMC6258910
OpenAlexW2902174064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.