Evidence map›Paper›PMID 30482745›Full record

ArticleCancer immunology research2019

Derek J Theisen, Stephen T Ferris, Carlos G Briseño, Nicole Kretzer, Arifumi Iwata, Kenneth M Murphy, Theresa L Murphy

Open access · greenAbstract read
In one paragraph

Article in Cancer immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 62 citations in OpenAlex.

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  14. DNA hypomethylation ameliorates erosive inflammatory arthritis by modulating interferon regulatory factor-8.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Derek J TheisenDepartment of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, Missouri.ORCID 0000-0002-2204-8676
Stephen T FerrisDepartment of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, Missouri.
Carlos G BriseñoDepartment of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, Missouri.
Nicole KretzerDepartment of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, Missouri.
Arifumi IwataDepartment of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, Missouri.
Kenneth M MurphyDepartment of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, Missouri.ORCID 0000-0002-3505-9630
Theresa L MurphyDepartment of Pathology and Immunology, Washington University in St. Louis, School of Medicine, St. Louis, Missouri. tmurphy@wustl.edu.ORCID 0000-0002-3505-9630
Washington University in St. Louis · USHoward Hughes Medical Institute · US

Funding

Molecular Basis of cDC1 DevelopmentR01AI162643 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2022 to 2025
$2.8M
Function of Wdfy4 in cross-presentation and immunityR01AI150297 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2019 to 2023
$2.5M
Understanding the Mechanisms of DC Licensing in CD8 T Cell PrimingR01CA248919 · NCI · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2021 to 2025
$2.3M
Role of WDFY4 in Treg developmentR01AI191447 · NIAID · WASHINGTON UNIVERSITY · PI CHYI S HSIEH, Kenneth M Murphy · 2025 to 2026
$1.5M
Mechanism of c-MYC repression by IRF8 in myeloid lineagesR21AI164142 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2021 to 2022
$433k
Transcriptional basis of embryonic macrophage developmentR21AI163421 · NIAID · WASHINGTON UNIVERSITY · PI MURPHY, KENNETH M · 2022 to 2023
$430k
Howard Hughes Medical InstituteNCI NIH HHS R01 CA248919NIAID NIH HHS R01 AI150297NIAID NIH HHS R01 AI162643NIAID NIH HHS R01 AI191447NIAID NIH HHS R21 AI163421NIAID NIH HHS R21 AI164142
6 · The paper itself

Abstract

The BATF3-dependent cDC1 lineage of conventional dendritic cells (cDC) is required for rejection of immunogenic sarcomas and for rejection of progressive sarcomas during checkpoint blockade therapy. One unique function of the cDC1 lineage is the efficient cross-presentation of tumor-derived neoantigens to CD8

Indexed as

AnimalsBasic-Leucine Zipper Transcription FactorsCell Line, TumorDendritic CellsFemaleFibrosarcomaGraft RejectionInterferon Regulatory Factor-8Interferon Regulatory FactorsLymph NodesMaleMice, Inbred C57BLMice, KnockoutOligonucleotide Array Sequence AnalysisRepressor ProteinsSpleenBasic-Leucine Zipper Transcription FactorsInterferon Regulatory Factor-8Interferon Regulatory FactorsRepressor ProteinsSNFT protein, mouse

Identifiers

PMID30482745
PMCPMC12093468
OpenAlexW2902555145

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.