Evidence map›Paper›PMID 30482586›Full record

ArticleEnvironment international2018

Nano-metal oxides induce antimicrobial resistance via radical-mediated mutagenesis.

Ye Zhang, April Z Gu, Shanshan Xie, Xiangyang Li, Tianyu Cen, Dan Li, Jianmin Chen

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Environment international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 81 citations in OpenAlex.

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  12. Evaluation of the Effects of Ag, Cu, ZnO and TiOInternational journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ye ZhangShanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP(3)), Department of Environmental Science and Engineering, Fudan University, Shanghai 200433, China.
April Z GuSchool of Civil and Environmental Engineering, Cornell University, Ithaca, NY 14853, United States.
Shanshan XieShanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP(3)), Department of Environmental Science and Engineering, Fudan University, Shanghai 200433, China.
Xiangyang LiShanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP(3)), Department of Environmental Science and Engineering, Fudan University, Shanghai 200433, China.
Tianyu CenShanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP(3)), Department of Environmental Science and Engineering, Fudan University, Shanghai 200433, China.
Dan LiShanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP(3)), Department of Environmental Science and Engineering, Fudan University, Shanghai 200433, China. Electronic address: lidanfudan@fudan.edu.cn.
Jianmin ChenShanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP(3)), Department of Environmental Science and Engineering, Fudan University, Shanghai 200433, China.
Fudan University · CNCornell University · US

Funding

EPA R836155C002Intramural EPA EPA999999
6 · The paper itself

Abstract

The widespread use of nanoparticles has triggered increasing concern and interest due to the adverse effects on global public health and environmental safety. Whether the presence of nano-metal oxides (NMOs) could facilitate the formation of new antimicrobial resistance genes (ARGs) via de novo mutation is largely unknown. Here, we proved that two widely used NMOs could significantly improve the mutation frequencies of CIP- and CHL-resistant E. coli isolates; however, the corresponding metal ions have weaker effects. Distinct concentration-dependent increases of 1.0-14.2 and 1.1-456.3 folds were observed in the resistance mutations after treatment with 0.16-100 mg/L nano-Al

Indexed as

Metal NanoparticlesMutagenesisAnti-Bacterial AgentsDNA DamageDrug Resistance, BacterialEscherichia coliOxidesReactive Oxygen SpeciesAnti-Bacterial AgentsOxidesReactive Oxygen SpeciesAntimicrobial resistance genes (ARGs)Genic mutationNano-metal oxidesReactive oxygen species (ROS)SOS response

Identifiers

PMID30482586
OpenAlexW2898491029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.